Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH3 | Q9Y5N1 | 4/20 | 0.44 |
| ▸ | MEN1 | O00255 | 2/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | HRH1 | P35367 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.38 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | PSMB1 | P20618 | 2/20 | 0.37 |
| ▸ | PSMB5 | P28074 | 2/20 | 0.37 |
| ▸ | PSMB2 | P49721 | 2/20 | 0.37 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.36 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.36 |
| ▸ | DRD3 | P35462 | 1/20 | 0.36 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.36 |
| ▸ | MITF | O75030 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8717062 | 0.84 | CYP2B6 (0.47) | HRH3MEN1KMT2ANPSR1KDM4E | |
| SCHEMBL8351139 | 0.81 | HRH3 (0.47) | HRH3MEN1KMT2AHRH1TSHR | |
| SCHEMBL8717430 | 0.77 | ALDH1A1 (0.37) | HRH1NPSR1KDM4ESMN1; SMN2ALDH1A1 | |
| SCHEMBL8353927 | 0.71 | MEN1 (0.57) | HRH3MEN1KMT2AHRH1NPSR1 | |
| SCHEMBL12038270 | 0.70 | TSHR (0.50) | MEN1KMT2ATSHRRAB9A | |
| SCHEMBL17018523 | 0.70 | TSHR (0.50) | TSHRRAB9A | |
| SCHEMBL20976187 | 0.69 | GAA (0.53) | MEN1KMT2ASIGMAR1SMN1; SMN2ALDH1A1 | |
| SCHEMBL4632546 | 0.69 | GAA (0.53) | MEN1KMT2ASIGMAR1SMN1; SMN2ALDH1A1 | |
| SCHEMBL14347905 | 0.68 | ALPL (0.47) | HRH3MEN1KMT2ATSHRNPSR1 | |
| SCHEMBL12828096 | 0.67 | TSHR (0.46) | TSHRRAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0569802-B1 | Arylacetamides | MERCK PATENT GMBH (DE) | 1998-07-15 | — | — | EP | disclosed |
| EP-0569802-A1 | Arylacetamides | MERCK PATENT GmbH (DE) | 1993-11-18 | — | — | EP | disclosed |