SCHEMBL8717337

SCHEMBL8717337

C=C(C=CC(=O)O)C(N)=O

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TSHR P16473 5/20 0.50
TP53 P04637 1/20 0.50
EGLN1 Q9GZT9 1/20 0.50
EGLN3 Q9H6Z9 1/20 0.50
TDP1 Q9NUW8 3/20 0.36
GABRR1 P24046 2/20 0.36
GABRR2 P28476 2/20 0.36
BLM P54132 2/20 0.36
LMNA P02545 2/20 0.36
GABRR3 A8MPY1 1/20 0.36
APEX1 P27695 1/20 0.36
NPSR1 Q6W5P4 1/20 0.36
ALDH1A1 P00352 3/20 0.36
CYP2C9 P11712 2/20 0.36
CYP1A2 P05177 1/20 0.36
MAPT P10636 1/20 0.36
HPGD P15428 1/20 0.36
CYP2C19 P33261 1/20 0.36
HSD17B10 Q99714 1/20 0.36
LDHA P00338 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Maleic Acid SCHEMBL28104651 0.78 TDP1 (0.67) TSHRTP53EGLN1EGLN3TDP1
SCHEMBL10526580 0.78 ALDH1A1 (0.38) TSHRTDP1ALDH1A1FGFR4
SCHEMBL8147344 0.77 TDP1 (0.40) TSHRTDP1ALDH1A1LDHALDHB
SCHEMBL4277537 0.77
SCHEMBL8147347 0.77 TDP1 (0.40) TSHRTDP1ALDH1A1LDHALDHB
SCHEMBL23457792 0.77
SCHEMBL119205 0.77 TSHR (0.56) TSHRTP53EGLN1EGLN3TDP1
SCHEMBL17324909 0.77 TSHR (0.56) TSHRTP53EGLN1EGLN3TDP1
Maleic Acid SCHEMBL15239556 0.75 TSHR (0.75) TSHRTP53EGLN1EGLN3TDP1
Fumaric Acid SCHEMBL365675 0.75 TSHR (0.75) TSHRTP53EGLN1EGLN3TDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5768090-A Bipolar electrochemical charge storage devices and a method of fabricating the same MOTOROLA, INC. (US) 1998-06-16 US claimed
WO-1998025282-A1 BIPOLAR ELECTROCHEMICAL CHARGE STORAGE DEVICES MOTOROLA INC. (US) 1998-06-11 WO claimed
US-5688614-A BETWEEN METALLIC ELECTRODES MOTOROLA, INC. (US) 1997-11-18 US claimed
WO-1997041611-A1 ELECTROCHEMICAL CELL HAVING A MULTI-LAYERED POLYMER ELECTROLYTE MOTOROLA INC. (US) 1997-11-06 WO claimed
US-5768090-A Bipolar electrochemical charge storage devices and a method of fabricating the same MOTOROLA, INC. (US) 1998-06-16 US disclosed
WO-1998025282-A1 BIPOLAR ELECTROCHEMICAL CHARGE STORAGE DEVICES MOTOROLA INC. (US) 1998-06-11 WO disclosed
US-5688614-A BETWEEN METALLIC ELECTRODES MOTOROLA, INC. (US) 1997-11-18 US disclosed
WO-1997041611-A1 ELECTROCHEMICAL CELL HAVING A MULTI-LAYERED POLYMER ELECTROLYTE MOTOROLA INC. (US) 1997-11-06 WO disclosed
US-4013606-A FROM CATIONIC FORMALDEHYDE ADDUCT AND VINYL POLYMER NALCO CHEMICAL COMPANY (US) 1977-03-22 US disclosed