Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | IDO1 | P14902 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8720104 | 0.85 | GAA (0.42) | GAAMAPTIDO1L3MBTL1 | |
| SCHEMBL8717650 | 0.80 | GAA (0.39) | GAAMAPTIDO1L3MBTL1 | |
| SCHEMBL8720177 | 0.79 | GAA (0.38) | GAAMAPTIDO1L3MBTL1 | |
| SCHEMBL8717628 | 0.78 | GAA (0.37) | GAAMAPTIDO1L3MBTL1 | |
| SCHEMBL7066158 | 0.78 | LATS1 (0.39) | GAAMAPTIDO1L3MBTL1 | |
| SCHEMBL7067988 | 0.77 | GAA (0.44) | GAAMAPTIDO1L3MBTL1 | |
| SCHEMBL8717908 | 0.77 | GAA (0.36) | GAAMAPTIDO1L3MBTL1 | |
| SCHEMBL7067970 | 0.77 | GAA (0.36) | GAAMAPTIDO1L3MBTL1 | |
| SCHEMBL8722401 | 0.77 | GAA (0.41) | GAAMAPTIDO1L3MBTL1 | |
| SCHEMBL8717871 | 0.76 | GAA (0.35) | GAAMAPTIDO1L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0877748-A1 | PYRIDO-1,2,4-THIADIAZINE AND PYRIDO-1,4-THIAZINE DERIVATIVES, THEIR PREPARATION AND USE | NOVO NORDISK A/S (DK) | 1998-11-18 | — | — | EP | disclosed |
| WO-1997026264-A1 | PYRIDO-1,2,4-THIADIAZINE AND PYRIDO-1,4-THIAZINE DERIVATIVES, THEIR PREPARATION AND USE | NOVO NORDISK A/S (DK) | 1997-07-24 | — | — | WO | disclosed |