SCHEMBL7066158

SCHEMBL7066158

CC(O)C(C)NC1=NSc2cnccc2N1

nearest known ligand 0.39

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
LATS1 O95835 1/20 0.39
LATS2 Q9NRM7 1/20 0.39
GAA P10253 1/20 0.37
MAPT P10636 1/20 0.37
IDO1 P14902 1/20 0.37
L3MBTL1 Q9Y468 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8720086 0.83 GAA (0.35) GAAMAPTIDO1L3MBTL1
SCHEMBL8717293 0.83 GAA (0.35) LATS1LATS2GAAMAPTIDO1
SCHEMBL7067970 0.83 GAA (0.36) GAAMAPTIDO1L3MBTL1
SCHEMBL7068588 0.79 KDM4C (0.43) LATS1LATS2GAAMAPTIDO1
SCHEMBL7069716 0.79 KDM4C (0.43) LATS1LATS2GAAMAPTIDO1
SCHEMBL7068593 0.79 KDM4C (0.43) LATS1LATS2GAAMAPTIDO1
SCHEMBL8717871 0.79 GAA (0.35) LATS1LATS2GAAMAPTIDO1
SCHEMBL7067988 0.78 GAA (0.44) GAAMAPTIDO1L3MBTL1
SCHEMBL7066155 0.78 HCAR3 (0.36) GAAMAPTIDO1L3MBTL1
SCHEMBL8717375 0.78 GAA (0.39) GAAMAPTIDO1L3MBTL1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2003045954-A1 USE OF SELECTIVE POTASSIUM CHANNEL OPENERS NOVO NORDISK A/S (DK) 2003-06-05 WO claimed