Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 3/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 3/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
| ▸ | TACR1 | P25103 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | CNR1 | P21554 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | IDO1 | P14902 | 2/20 | 0.38 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.38 |
| ▸ | SLC6A2 | P23975 | 3/20 | 0.38 |
| ▸ | SLC6A4 | P31645 | 3/20 | 0.38 |
| ▸ | SLC6A3 | Q01959 | 3/20 | 0.38 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8717462 | 1.00 | KMT2A (0.41) | KMT2AMEN1CYP2D6CYP3A4LMNA | |
| SCHEMBL8720035 | 0.89 | ATM (0.46) | KMT2AMEN1CYP2D6LMNAALDH1A1 | |
| SCHEMBL8720039 | 0.89 | ATM (0.46) | KMT2AMEN1CYP2D6LMNAALDH1A1 | |
| SCHEMBL8713544 | 0.88 | SMN1; SMN2 (0.41) | KMT2ACYP2D6CYP3A4LMNAALDH1A1 | |
| SCHEMBL8713546 | 0.88 | SMN1; SMN2 (0.41) | KMT2ACYP2D6CYP3A4LMNAALDH1A1 | |
| SCHEMBL8720148 | 0.86 | ADRB3 (0.44) | KMT2AMEN1 | |
| SCHEMBL8720151 | 0.86 | ADRB3 (0.44) | KMT2AMEN1 | |
| SCHEMBL8714398 | 0.86 | SLC6A4 (0.49) | CYP2D6CYP3A4SLC6A2SLC6A4SLC6A3 | |
| SCHEMBL8714400 | 0.86 | SLC6A4 (0.49) | CYP2D6CYP3A4SLC6A2SLC6A4SLC6A3 | |
| SCHEMBL8715306 | 0.84 | MEN1 (0.40) | KMT2AMEN1CYP2D6SLC6A2SLC6A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5811293-A | CULTURE PRODUCT AS CHEMICAL INTERMEDIATE FOR ANTI-OBESITY AGENT | DAICEL CHEMICAL INDUSTRIES, LTD. (JP) | 1998-09-22 | — | — | US | disclosed |