Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ATM | Q13315 | 1/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 2/20 | 0.45 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.45 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.45 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.44 |
| ▸ | MEN1 | O00255 | 3/20 | 0.44 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.44 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.44 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.44 |
| ▸ | HTR7 | P34969 | 1/20 | 0.44 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.44 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.44 |
| ▸ | BCHE | P06276 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | CRHBP | P24387 | 1/20 | 0.43 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.43 |
| ▸ | IDO1 | P14902 | 2/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8720039 | 1.00 | ATM (0.46) | ATML3MBTL1LMNAADRA2AADRA2C | |
| SCHEMBL8713546 | 0.91 | SMN1; SMN2 (0.41) | LMNAKMT2ACYP2D6SLC6A2SLC6A4 | |
| SCHEMBL8713544 | 0.91 | SMN1; SMN2 (0.41) | LMNAKMT2ACYP2D6SLC6A2SLC6A4 | |
| SCHEMBL8717462 | 0.89 | KMT2A (0.41) | LMNAKDM4EKMT2AMEN1CYP2D6 | |
| SCHEMBL8717465 | 0.89 | KMT2A (0.41) | LMNAKDM4EKMT2AMEN1CYP2D6 | |
| SCHEMBL8717141 | 0.87 | AOC3 (0.39) | ATML3MBTL1KMT2AMEN1CYP2D6 | |
| SCHEMBL8717142 | 0.87 | AOC3 (0.39) | ATML3MBTL1KMT2AMEN1CYP2D6 | |
| SCHEMBL8716176 | 0.87 | IDO1 (0.42) | LMNAADRA2AKMT2AMEN1CYP2D6 | |
| SCHEMBL8716177 | 0.87 | IDO1 (0.42) | LMNAADRA2AKMT2AMEN1CYP2D6 | |
| SCHEMBL8715306 | 0.86 | MEN1 (0.40) | KMT2AMEN1CYP2D6SLC6A2SLC6A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5811293-A | CULTURE PRODUCT AS CHEMICAL INTERMEDIATE FOR ANTI-OBESITY AGENT | DAICEL CHEMICAL INDUSTRIES, LTD. (JP) | 1998-09-22 | — | — | US | disclosed |