Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 2/20 | 0.81 |
| ▸ | POLG | P54098 | 2/20 | 0.78 |
| ▸ | POLA1 | P09884 | 1/20 | 0.78 |
| ▸ | PNP | P00491 | 6/20 | 0.67 |
| ▸ | HPRT1 | P00492 | 11/20 | 0.62 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8720393 | 0.94 | POLB (0.72) | POLBPOLGPOLA1PNPHPRT1 | |
| SCHEMBL9053987 | 0.93 | POLB (0.76) | POLBPOLGPOLA1PNPHPRT1 | |
| SCHEMBL17617679 | 0.91 | POLB (0.76) | POLBPOLGPOLA1PNPHPRT1 | |
| SCHEMBL8717128 | 0.90 | POLB (0.68) | POLBPOLGPOLA1PNPHPRT1 | |
| SCHEMBL9055784 | 0.90 | POLB (0.81) | POLBPOLGPOLA1PNPHPRT1 | |
| SCHEMBL19770654 | 0.88 | POLB (0.72) | POLBPOLGPOLA1PNPHPRT1 | |
| SCHEMBL13815860 | 0.88 | POLB (0.85) | POLBPOLGPOLA1PNPHPRT1 | |
| SCHEMBL30760008 | 0.88 | POLB (1.00) | POLBPOLGPOLA1PNPHPRT1 | |
| SCHEMBL16075000 | 0.88 | POLB (0.71) | POLBPOLGPOLA1PNPHPRT1 | |
| SCHEMBL16063241 | 0.88 | POLB (0.71) | POLBPOLGPOLA1PNPHPRT1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0269947-B2 | Antiviral phosphonomethoxyalkylene purine and pyrimidine derivatives | ACAD OF SCIENCE CZECH REPUBLIC (CS) | 1996-10-16 | — | — | EP | claimed |
| EP-0269947-A1 | Antiviral phosphonomethoxyalkylene purine and pyrimidine derivatives | INSTITUTE OF ORGANIC CHEMISTRY AND BIOCHEMISTRY OF THE ACADEMY OF SCIENCES OF THE CZECH REPUBLIC (CS) | 1988-06-08 | — | — | EP | claimed |
| US-5854228-A | Antiviral phosphonomethoxyalkylene purine and pyrimidine derivatives | INSTITUTE OF ORGANIC CHEMISTRY AND BIOCHEMISTRY OF THE ACADEMY OF SCIENCES OF THE CZECH REPUBLIC (CZ) | 1998-12-29 | — | — | US | disclosed |
| US-5650510-A | VIRICIDES OR ANTITUMOR AGENTS | INSTITUTE OF ORGANIC CHEMISTRY AND BIOCHEMISTRY OF THE ACADEMY OF SCIENCES OF THE CZECH REPUBLIC (CZ) | 1997-07-22 | — | — | US | disclosed |
| EP-0269947-B2 | Antiviral phosphonomethoxyalkylene purine and pyrimidine derivatives | ACAD OF SCIENCE CZECH REPUBLIC (CS) | 1996-10-16 | — | — | EP | disclosed |
| EP-0269947-A1 | Antiviral phosphonomethoxyalkylene purine and pyrimidine derivatives | INSTITUTE OF ORGANIC CHEMISTRY AND BIOCHEMISTRY OF THE ACADEMY OF SCIENCES OF THE CZECH REPUBLIC (CS) | 1988-06-08 | — | — | EP | disclosed |