Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IDO1 | P14902 | 2/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.32 |
| ▸ | LMNA | P02545 | 2/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.32 |
| ▸ | POLB | P06746 | 2/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.32 |
| ▸ | CHEK1 | O14757 | 2/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | MAOA | P21397 | 1/20 | 0.30 |
| ▸ | MAOB | P27338 | 1/20 | 0.30 |
| ▸ | F2 | P00734 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8720054 | 0.88 | IDO1 (0.42) | IDO1GAAMAPTL3MBTL1KDM4C | |
| SCHEMBL7069376 | 0.81 | GAA (0.43) | IDO1GAAMAPTL3MBTL1KDM4C | |
| SCHEMBL8584700 | 0.79 | NPC1 (0.38) | MAPTL3MBTL1MAPK1KMT2AALDH1A1 | |
| SCHEMBL8720440 | 0.79 | GAA (0.35) | IDO1GAAMAPTL3MBTL1 | |
| SCHEMBL8717891 | 0.78 | GAA (0.35) | IDO1GAAMAPTL3MBTL1KDM4C | |
| SCHEMBL8722401 | 0.77 | GAA (0.41) | IDO1GAAMAPTL3MBTL1 | |
| SCHEMBL6618067 | 0.73 | NAMPT (0.37) | KDM4CLMNAKMT2APOLBTDP1 | |
| SCHEMBL8720104 | 0.71 | GAA (0.42) | IDO1GAAMAPTL3MBTL1 | |
| SCHEMBL7068593 | 0.71 | KDM4C (0.43) | IDO1GAAMAPTL3MBTL1KDM4C | |
| SCHEMBL8722364 | 0.71 | KDM4D (0.46) | IDO1GAAMAPTL3MBTL1KDM4C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0877748-A1 | PYRIDO-1,2,4-THIADIAZINE AND PYRIDO-1,4-THIAZINE DERIVATIVES, THEIR PREPARATION AND USE | NOVO NORDISK A/S (DK) | 1998-11-18 | — | — | EP | disclosed |
| WO-1997026264-A1 | PYRIDO-1,2,4-THIADIAZINE AND PYRIDO-1,4-THIAZINE DERIVATIVES, THEIR PREPARATION AND USE | NOVO NORDISK A/S (DK) | 1997-07-24 | — | — | WO | disclosed |