Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4D | Q6B0I6 | 1/20 | 0.46 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.46 |
| ▸ | NAMPT | P43490 | 3/20 | 0.46 |
| ▸ | JAK2 | O60674 | 1/20 | 0.46 |
| ▸ | TYK2 | P29597 | 1/20 | 0.46 |
| ▸ | RAB9A | P51151 | 4/20 | 0.43 |
| ▸ | GAA | P10253 | 3/20 | 0.43 |
| ▸ | NPC1 | O15118 | 3/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | MAPT | P10636 | 2/20 | 0.43 |
| ▸ | STAT3 | P40763 | 2/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | KCNK3 | O14649 | 2/20 | 0.42 |
| ▸ | IDO1 | P14902 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | BCAT2 | O15382 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6617628 | 0.73 | KDM4D (0.45) | KDM4DKDM4CNAMPTJAK2TYK2 | |
| SCHEMBL8720104 | 0.72 | GAA (0.42) | GAAMAPTIDO1L3MBTL1 | |
| SCHEMBL8720054 | 0.69 | IDO1 (0.42) | KDM4DKDM4CGAAMAPTKDM4E | |
| SCHEMBL7834450 | 0.68 | BRD4 (0.43) | RAB9AGAANPC1KMT2AMAPT | |
| SCHEMBL28561950 | 0.67 | KDM4D (0.69) | KDM4DKDM4CNAMPTJAK2TYK2 | |
| SCHEMBL8717628 | 0.66 | GAA (0.37) | GAAMAPTIDO1L3MBTL1 | |
| SCHEMBL18293133 | 0.65 | MEN1 (0.55) | NAMPTJAK2TYK2RAB9AGAA | |
| SCHEMBL8717908 | 0.65 | GAA (0.36) | GAAMAPTKDM4EIDO1L3MBTL1 | |
| SCHEMBL13740469 | 0.64 | KDM4D (0.65) | KDM4DKDM4CNAMPTJAK2TYK2 | |
| SCHEMBL15093653 | 0.64 | NPC1 (0.72) | RAB9ANPC1KMT2ASMN1; SMN2MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1208418-A | Pyrido-1, 2, 4-thiadiazine and pyrido-1, 4-thiazine derivatives, preparation method and application thereof | NOVO NORDISK AS (DK) | 1999-02-17 | — | — | CN | disclosed |
| EP-0877748-A1 | PYRIDO-1,2,4-THIADIAZINE AND PYRIDO-1,4-THIAZINE DERIVATIVES, THEIR PREPARATION AND USE | NOVO NORDISK A/S (DK) | 1998-11-18 | — | — | EP | disclosed |
| WO-1997026264-A1 | PYRIDO-1,2,4-THIADIAZINE AND PYRIDO-1,4-THIAZINE DERIVATIVES, THEIR PREPARATION AND USE | NOVO NORDISK A/S (DK) | 1997-07-24 | — | — | WO | disclosed |