SCHEMBL8717811

SCHEMBL8717811

NCCc1cc2cc(Cl)ccc2o1

nearest known ligand 0.49

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP19A1 P11511 1/20 0.49
MAOB P27338 3/20 0.47
F2 P00734 1/20 0.46
F10 P00742 1/20 0.46
KDM4E B2RXH2 4/20 0.44
CA12 O43570 1/20 0.44
CA1 P00915 1/20 0.44
CA2 P00918 1/20 0.44
CA9 Q16790 1/20 0.44
LOXL2 Q9Y4K0 1/20 0.42
GPR35 Q9HC97 2/20 0.41
CYP1A2 P05177 2/20 0.41
ALDH1A1 P00352 1/20 0.41
CYP2C9 P11712 1/20 0.41
L3MBTL1 Q9Y468 1/20 0.41
KMT2A Q03164 1/20 0.41
MMP2 P08253 1/20 0.40
MMP9 P14780 1/20 0.40
ADAM17 P78536 1/20 0.40
NPC1 O15118 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Hydrochloric Acid SCHEMBL22395344 0.98 CYP19A1 (0.48) CYP19A1MAOBF2F10KDM4E
SCHEMBL10674648 0.86 LOXL2 (0.42) CYP19A1MAOBF2F10CA12
SCHEMBL15708027 0.85 LOXL2 (0.58) CYP19A1MAOBF2F10KDM4E
SCHEMBL29988206 0.85 LOXL2 (0.58) CYP19A1MAOBF2F10KDM4E
SCHEMBL11190838 0.82 CYP19A1 (0.49) CYP19A1MAOBF2F10KDM4E
SCHEMBL361904 0.79 CYP19A1 (0.53) CYP19A1MAOBKDM4ECA12CA1
SCHEMBL29779144 0.79 CYP19A1 (0.53) CYP19A1MAOBKDM4ECA12CA1
SCHEMBL2331524 0.79 KMT2A (0.55) CYP19A1MAOBF2F10KDM4E
SCHEMBL10729516 0.79 F2 (0.46) MAOBF2F10CA12CA1
SCHEMBL8950183 0.79 CYP19A1 (0.49) CYP19A1F2F10CA12CA1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5814669-A REACTING A PHENETHYLAMINE WITH 4-ISOPROPYL-2,5-OXAZOLIDINEDIONE; APPLYING TO PLANT, SOIL OR SEED BAYER AKTIENGESELLSCHAFT (DE) 1998-09-29 US disclosed
EP-0767780-A1 AMINO ACID DERIVATIVES AND THEIR USE AS PESTICIDES BAYER AG (DE) 1997-04-16 EP disclosed
WO-1996000718-A1 AMINO ACID DERIVATIVES AND THEIR USE AS PESTICIDES BAYER AKTIENGESELLSCHAFT (DE) 1996-01-11 WO disclosed
EP-0283522-B1 TRIAZINE DERIVATIVE, PRODUCTION THEREOF, AND HERBICIDE CONTAINING SAME AS EFFECTIVE INGREDIENT IDEMITSU KOSAN COMPANY LIMITED (JP) 1991-02-27 EP disclosed