SCHEMBL8717878

SCHEMBL8717878

NCC(=O)NCC(=O)N[C@@H](CC(N)=O)C(=O)N[C@@H](CC(N)=O)C(=O)N[C@@H](CC(N)=O)C(=O)N[C@@H](CC(N)=O)C(=O)O

nearest known ligand 0.47

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
ECE1 P42892 3/20 0.47
MEN1 O00255 1/20 0.41
KMT2A Q03164 1/20 0.41
ALDH1A1 P00352 1/20 0.39
RAB9A P51151 1/20 0.39
ITGB2 P05107 1/20 0.38
ICAM1 P05362 1/20 0.38
ITGAL P20701 1/20 0.38
CA2 P00918 4/20 0.36
CA1 P00915 2/20 0.36
QRFPR Q96P65 3/20 0.36
PDCD1LG2 Q9BQ51 1/20 0.35
CD274 Q9NZQ7 1/20 0.35
CTSB P07858 2/20 0.35
TERT O14746 1/20 0.35
CA4 P22748 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL901075 1.00 ECE1 (0.47) ECE1MEN1KMT2AALDH1A1RAB9A
SCHEMBL5852103 1.00 ECE1 (0.47) ECE1MEN1KMT2AALDH1A1RAB9A
SCHEMBL9389801 0.98 ECE1 (0.46) ECE1MEN1KMT2AALDH1A1RAB9A
SCHEMBL8030981 0.98 ECE1 (0.46) ECE1MEN1KMT2AALDH1A1RAB9A
SCHEMBL7025870 0.98 ECE1 (0.46) ECE1MEN1KMT2AALDH1A1RAB9A
SCHEMBL8427315 0.97 ECE1 (0.45) ECE1MEN1KMT2AALDH1A1RAB9A
SCHEMBL9228209 0.96 ECE1 (0.44) ECE1MEN1KMT2AALDH1A1RAB9A
SCHEMBL29630509 0.96 ECE1 (0.44) ECE1MEN1KMT2AALDH1A1RAB9A
SCHEMBL8717867 0.96 ECE1 (0.44) ECE1MEN1KMT2AALDH1A1RAB9A
SCHEMBL8717768 0.96 ECE1 (0.44) ECE1MEN1KMT2AALDH1A1RAB9A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 24 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5763254-A ENDOGENOUS TO STRAIN OF FUNGUS OTHER THAN TRICHODERMA OR PHANEROCHAETE NOVO NORDISK A/S (DK) 1998-06-09 US claimed
US-5457046-A Polypeptides NOVO NORDISK A/S (DK) 1995-10-10 US claimed
EP-0531315-A1 AN ENZYME CAPABLE OF DEGRADING CELLULOSE OR HEMICELLULOSE. NOVO NORDISK AS (DK) 1993-03-17 EP claimed
WO-1991017244-A1 AN ENZYME CAPABLE OF DEGRADING CELLULOSE OR HEMICELLULOSE NOVO NORDISK A/S (DK) 1991-11-14 WO claimed
CN-110582567-B Genetically modified trehalase-expressing yeasts and fermentation methods using such genetically modified yeasts 嘉吉公司 2024-03-08 CN disclosed
CN-112126606-B Photobacterium QA16 and culture method and application thereof 山东大学 2022-09-30 CN disclosed
CN-114478796-A Modified human immunodeficiency virus membrane protein and application thereof 厦门大学 2022-05-13 CN disclosed
CN-112126606-A Photobacterium QA16 and culture method and application thereof 山东大学 2020-12-25 CN disclosed
CN-110582567-A Genetically modified trehalase-expressing yeast and fermentation process using such genetically modified yeast 嘉吉公司 2019-12-17 CN disclosed
CN-110582295-A Multiple malaria pre-erythroid antigens and their use to elicit a protective immune response in a host 巴斯德研究所 2019-12-17 CN disclosed
CN-101166830-A Hydrolysis of arabinoxylan NOVOZYMES AS (DK) 2008-04-23 CN disclosed
CN-1918277-A Saccharification process NOVOZYMES AS (DK) 2007-02-21 CN disclosed
US-5457046-A Polypeptides NOVO NORDISK A/S (DK) 1995-10-10 US disclosed
WO-1994023746-A1 PEPTIDES FOR USE IN VACCINATION AND INDUCTION OF NEUTRALIZING ANTIBODIES AGAINST HUMAN IMMUNODEFICIENCY VIRUS SYNTELLO VACCINE DEVELOPMENT AB (SE) 1994-10-27 WO disclosed
EP-0531315-A1 AN ENZYME CAPABLE OF DEGRADING CELLULOSE OR HEMICELLULOSE. NOVO NORDISK AS (DK) 1993-03-17 EP disclosed
EP-0527760-A1 METHODS AND COMPOSITIONS FOR VACCINATION AGAINST HIV. GENENTECH INC (US) 1993-02-24 EP disclosed
EP-0527789-A1 HIV ENVELOPE POLYPEPTIDES GENENTECH, INC. (US) 1993-02-24 EP disclosed
WO-1991017244-A1 AN ENZYME CAPABLE OF DEGRADING CELLULOSE OR HEMICELLULOSE NOVO NORDISK A/S (DK) 1991-11-14 WO disclosed
WO-1991015238-A1 METHODS AND COMPOSITIONS FOR VACCINATION AGAINST HIV GENENTECH, INC. (US) 1991-10-17 WO disclosed
WO-1991015512-A2 HIV ENVELOPE POLYPEPTIDES GENENTECH, INC. (US) 1991-10-17 WO disclosed