Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC18A3 | Q16572 | 1/20 | 0.42 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.42 |
| ▸ | KDM1A | O60341 | 4/20 | 0.41 |
| ▸ | MAOA | P21397 | 4/20 | 0.41 |
| ▸ | MAOB | P27338 | 4/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | PKM | P14618 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 2/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | JAK3 | P52333 | 1/20 | 0.35 |
| ▸ | USP2 | O75604 | 1/20 | 0.35 |
| ▸ | SSTR4 | P31391 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17948228 | 0.78 | SLC18A3 (0.48) | SLC18A3SIGMAR1KDM1AMAOAMAOB | |
| SCHEMBL317325 | 0.77 | TRPA1 (0.46) | SLC18A3KDM1AMAOAMAOBMAPK1 | |
| SCHEMBL14045495 | 0.75 | KDM1A (0.53) | KDM1AMAOAMAOBMAPK1CYP2C19 | |
| SCHEMBL13556691 | 0.75 | KDM1A (0.53) | KDM1AMAOAMAOBMAPK1CYP2C19 | |
| SCHEMBL15766923 | 0.75 | KDM1A (0.53) | KDM1AMAOAMAOBMAPK1CYP2C19 | |
| SCHEMBL15541000 | 0.75 | KDM1A (0.53) | KDM1AMAOAMAOBMAPK1CYP2C19 | |
| SCHEMBL3530324 | 0.75 | KDM1A (0.53) | KDM1AMAOAMAOBMAPK1CYP2C19 | |
| SCHEMBL5009519 | 0.75 | KDM1A (0.42) | SLC18A3SIGMAR1KDM1AMAOAMAOB | |
| SCHEMBL23646349 | 0.70 | KDM1A (0.40) | KDM1AMAOAMAOBMAPK1CYP2C19 | |
| SCHEMBL27658364 | 0.70 | SLC18A3 (0.38) | SLC18A3SIGMAR1KDM1AMAOAMAOB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0828735-A1 | PROCESS FOR PREPARING 4-ARYL-PIPERIDINE DERIVATIVES | NOVO NORDISK A/S (DK) | 1998-03-18 | — | — | EP | disclosed |
| WO-1996036636-A1 | PROCESS FOR PREPARING 4-ARYL-PIPERIDINE DERIVATIVES | NOVO NORDISK A/S (DK) | 1996-11-21 | — | — | WO | disclosed |