Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2C9 | P11712 | 3/20 | 0.44 |
| ▸ | MAPT | P10636 | 2/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 4/20 | 0.42 |
| ▸ | APP | P05067 | 2/20 | 0.40 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
| ▸ | FASN | P49327 | 1/20 | 0.38 |
| ▸ | ESR2 | Q92731 | 2/20 | 0.38 |
| ▸ | RARB | P10826 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | SPHK1 | Q9NYA1 | 5/20 | 0.36 |
| ▸ | CYP2C8 | P10632 | 1/20 | 0.35 |
| ▸ | S1PR3 | Q99500 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13433633 | 1.00 | CYP2C9 (0.44) | CYP2C9MAPTALDH1A1LMNAMEN1 | |
| SCHEMBL8652988 | 1.00 | CYP2C9 (0.44) | CYP2C9MAPTALDH1A1LMNAMEN1 | |
| SCHEMBL8652983 | 1.00 | CYP2C9 (0.44) | CYP2C9MAPTALDH1A1LMNAMEN1 | |
| SCHEMBL739937 | 1.00 | CYP2C9 (0.44) | CYP2C9MAPTALDH1A1LMNAMEN1 | |
| SCHEMBL4799680 | 0.97 | CYP3A4 (0.44) | CYP2C9MAPTALDH1A1LMNAMEN1 | |
| SCHEMBL8831427 | 0.97 | CYP3A4 (0.44) | CYP2C9MAPTALDH1A1LMNAMEN1 | |
| SCHEMBL7759051 | 0.97 | CYP3A4 (0.44) | CYP2C9MAPTALDH1A1LMNAMEN1 | |
| SCHEMBL4799678 | 0.97 | CYP3A4 (0.44) | CYP2C9MAPTALDH1A1LMNAMEN1 | |
| SCHEMBL10043218 | 0.96 | CYP2C9 (0.41) | CYP2C9MAPTALDH1A1LMNAMEN1 | |
| SCHEMBL10043244 | 0.96 | CYP2C9 (0.41) | CYP2C9MAPTALDH1A1LMNAMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 142 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8470199-B2 | Five-ring liquid crystal compound, liquid crystal composition and liquid crystal display device | JNC CORPORATION (JP) | 2013-06-25 | — | — | US | disclosed |
| US-20120074355-A1 | FIVE-RING LIQUID CRYSTAL COMPOUND, LIQUID CRYSTAL COMPOSITION AND LIQUID CRYSTAL DISPLAY DEVICE | JNC PETROCHEMICAL CORPORATION (JP) | 2012-03-29 | — | — | US | disclosed |
| US-7445818-B2 | Matrix liquid crystal display | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 2008-11-04 | — | — | US | disclosed |
| US-20070275182-A1 | Matrix liquid crystal display | WEBER GEORG | 2007-11-29 | — | — | US | disclosed |
| US-7186447-B2 | Two plane parallel support plates with frame form cell, with integrated non-linear elements for switching individual picture elements on support plates, and nematic liquid crystal mixture is present in cell, having positive dielectric anisotropy and high resistivity | MERCK PATENT GMBH (DE) | 2007-03-06 | — | — | US | disclosed |
| US-20050196551-A1 | Matrix liquid crystal display | WEBER GEORG (DE) | 2005-09-08 | — | — | US | disclosed |
| US-6905740-B2 | The invention relates to a matrix liquid crystal display containing integrated non-linear elements and a liquid crystal mixture which has a particularly high resistivity. | MERCK PATENT GMBH (DE) | 2005-06-14 | — | — | US | disclosed |
| US-20030207046-A1 | Matrix liquid crystal display | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 2003-11-06 | — | — | US | disclosed |
| US-6562419-B1 | Matrix liquid crystal display | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 2003-05-13 | — | — | US | disclosed |
| US-6210760-B1 | SHORT SWITCHING TIMES AND GRADIENTS AND ANGULAR DEPENDENCIES | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 2001-04-03 | — | — | US | disclosed |
| EP-0205503-A1 | LIQUID CRYSTALLINE PHASE. | MERCK PATENT GMBH (DE) | 1986-12-30 | — | — | EP | disclosed |
| EP-0199004-A1 | Pyrimidine derivatives | MERCK PATENT GmbH (DE) | 1986-10-29 | — | — | EP | disclosed |
| WO-1986005799-A1 | LIQUID CRYSTAL PHASE | MERCK Patent Gesellschaft mit beschränkter Haftung (DE) | 1986-10-09 | — | — | WO | disclosed |
| WO-1986004060-A1 | PYRIMIDINES | MERCK Patent Gesellschaft mit beschränkter Haftung (DE) | 1986-07-17 | — | — | WO | disclosed |
| WO-1986004081-A1 | LIQUID CRYSTALLINE PHASES | MERCK Patent Gesellschaft mit beschränkter Haftung (DE) | 1986-07-17 | — | — | WO | disclosed |
| WO-1986003769-A1 | LIQUID CRYSTALLINE PHASE | MERCK Patent Gesellschaft mit beschränkter Haftung (DE) | 1986-07-03 | — | — | WO | disclosed |
| EP-0158252-A2 | Liquid crystal phase | MERCK PATENT GmbH (DE) | 1985-10-16 | — | — | EP | disclosed |
| EP-0064193-B1 | 4,4'-BIS-(CYCLOHEXYL)-BIPHENYL DERIVATIVES THAT CONTAIN FLUORINE, DIELECTRICS CONTAINING THEM, AND ELECTRO-OPTICAL INDICATOR ELEMENT | MERCK PATENT GmbH (DE) | 1984-07-25 | — | — | EP | disclosed |
| US-4419264-A | Fluorine-containing 4,4'-bis-(cyclohexyl)-biphenyl derivatives, and dielectrics and electro-optical display elements containing them | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 1983-12-06 | — | — | US | disclosed |
| EP-0064193-A1 | 4,4'-Bis-(cyclohexyl)-biphenyl derivatives that contain fluorine, dielectrics containing them, and electro-optical indicator element | MERCK PATENT GmbH (DE) | 1982-11-10 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120074355-A1 | FIVE-RING LIQUID CRYSTAL COMPOUND, LIQUID CRYSTAL COMPOSITION AND LIQUID CRYSTAL DISPLAY DEVICE | HTR3D, KIF23, CCND3 | CYP2C9 3544/4885MAPT 667/4885ALDH1A1 1115/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.