Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TPSAB1 | Q15661 | 5/20 | 0.66 |
| ▸ | TPSD1 | Q9BZJ3 | 5/20 | 0.66 |
| ▸ | TPSG1 | Q9NRR2 | 5/20 | 0.66 |
| ▸ | MAPT | P10636 | 3/20 | 0.54 |
| ▸ | NPC1 | O15118 | 3/20 | 0.54 |
| ▸ | RAB9A | P51151 | 3/20 | 0.54 |
| ▸ | TSHR | P16473 | 2/20 | 0.54 |
| ▸ | MEN1 | O00255 | 2/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.54 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.54 |
| ▸ | CASP3 | P42574 | 1/20 | 0.54 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.54 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.54 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.54 |
| ▸ | F2 | P00734 | 6/20 | 0.52 |
| ▸ | PLAU | P00749 | 5/20 | 0.51 |
| ▸ | PLAT | P00750 | 4/20 | 0.51 |
| ▸ | PLG | P00747 | 3/20 | 0.51 |
| ▸ | KLKB1 | P03952 | 3/20 | 0.51 |
| ▸ | PRSS1 | P07477 | 3/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8718442 | 0.90 | TPSAB1 (0.54) | TPSAB1TPSD1TPSG1MAPTNPC1 | |
| SCHEMBL8718615 | 0.88 | TPSAB1 (0.52) | TPSAB1TPSD1TPSG1MAPTNPC1 | |
| SCHEMBL8717795 | 0.87 | F2 (0.57) | TPSAB1TPSD1TPSG1NPC1RAB9A | |
| SCHEMBL8713075 | 0.86 | NPC1 (0.52) | TPSAB1TPSD1TPSG1MAPTNPC1 | |
| SCHEMBL8718457 | 0.84 | PLG (0.55) | TPSAB1TPSD1TPSG1MAPTNPC1 | |
| SCHEMBL8718263 | 0.83 | MAPT (0.50) | TPSAB1TPSD1TPSG1MAPTNPC1 | |
| SCHEMBL8904054 | 0.81 | TPSAB1 (0.49) | TPSAB1TPSD1TPSG1MAPTNPC1 | |
| SCHEMBL8715620 | 0.80 | PLAU (0.47) | TPSAB1TPSD1TPSG1MAPTNPC1 | |
| SCHEMBL8903999 | 0.80 | MAPT (0.46) | TPSAB1TPSD1TPSG1MAPTNPC1 | |
| SCHEMBL8718226 | 0.79 | SMN1; SMN2 (0.52) | MAPTNPC1RAB9ATSHRMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5753670-A | ANTICOAGULANTS | THE GREEN CROSS CORPORATION (JP) | 1998-05-19 | — | — | US | disclosed |
| US-5635527-A | ANTAGONIST OF PLATELET MEMBRANE GLYCOPROTEIN; TREATMENT OF THROMBOTIC DISEASES | THE GREEN CROSS CORPORATION (JP) | 1997-06-03 | — | — | US | disclosed |
| EP-0712844-A1 | NOVEL FUSED-RING CARBOXYLIC ACID COMPOUND OR SALT THEREOF, AND MEDICINAL USE THEREOF | THE GREEN CROSS CORPORATION (JP) | 1996-05-22 | — | — | EP | disclosed |