SCHEMBL8718237

SCHEMBL8718237

CCN(CC)C(N(CC)CC)P(=O)(O)O

nearest known ligand 0.64

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
FDPS P14324 8/20 0.64
MMP2 P08253 2/20 0.44
MMP1 P03956 1/20 0.44
MMP3 P08254 1/20 0.44
MMP8 P22894 1/20 0.44
LAP3 P28838 2/20 0.40
METAP1 P53582 2/20 0.34
LPAR3 Q9UBY5 2/20 0.33
KDM4E B2RXH2 1/20 0.33
THRB P10828 1/20 0.33
MAPK1 P28482 1/20 0.33
HSD17B10 Q99714 1/20 0.33
LPAR2 Q9HBW0 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
(Diethylamino)Methylenediphosphonic Acid SCHEMBL9630354 0.78 FDPS (1.00) FDPSMMP2MMP1MMP3MMP8
SCHEMBL6886907 0.78 FDPS (0.64) FDPSMMP2MMP1MMP3MMP8
SCHEMBL2485107 0.77 FDPS (0.50) FDPSMMP2MMP1MMP3MMP8
SCHEMBL7079157 0.72 FDPS (0.77) FDPSMMP2MMP1MMP3MMP8
SCHEMBL10963444 0.69 FDPS (0.52) FDPSMMP2MMP1MMP3MMP8
Phosphoric Acid SCHEMBL28500442 0.69 FDPS (0.52) FDPSMMP2MMP1MMP3MMP8
SCHEMBL8470428 0.67 FDPS (0.68) FDPSMMP2MMP1MMP3MMP8
SCHEMBL17239410 0.67 FDPS (0.50) FDPSMMP2MMP1MMP3MMP8
SCHEMBL377182 0.67 FDPS (0.64) FDPSMMP2MMP1MMP3MMP8
SCHEMBL8983123 0.65 FDPS (0.61) FDPSMMP2MMP1MMP3MMP8

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-114249956-A Surface-modified metal oxide nanoparticle dispersion composition, method for producing same, film composition, and optical film 凯斯科技股份有限公司 2022-03-29 CN claimed
CN-114249956-A Surface-modified metal oxide nanoparticle dispersion composition, method for producing same, film composition, and optical film 凯斯科技股份有限公司 2022-03-29 CN disclosed
EP-0570380-B1 NOVEL METHYLENEBISPHOSPHONIC ACID DERIVATIVES LEIRAS OY (FI) 1998-09-16 EP disclosed
EP-0570380-A1 NOVEL METHYLENEBISPHOSPHONIC ACID DERIVATIVES LEIRAS OY (FI) 1993-11-24 EP disclosed
WO-1992011268-A1 NOVEL METHYLENEBISPHOSPHONIC ACID DERIVATIVES LEIRAS OY (FI) 1992-07-09 WO disclosed