SCHEMBL8718489

SCHEMBL8718489

CCCc1c(CC[Si](C)(Cl)Cl)c(CC[Si](C)(Cl)Cl)c(CC[Si](C)(Cl)Cl)c(CC[Si](C)(Cl)Cl)c1CC[Si](C)(Cl)Cl

nearest known ligand 0.31

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 1/20 0.31
ALDH1A1 P00352 1/20 0.31
GAA P10253 1/20 0.31
HPGD P15428 1/20 0.31
TYMP P19971 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8718506 1.00 KDM4E (0.31) KDM4EALDH1A1GAAHPGDTYMP
SCHEMBL18131683 0.89 ALDH1A1 (0.31) ALDH1A1
SCHEMBL8716473 0.85 NPC1 (0.34) HPGDTYMP
SCHEMBL8713563 0.85 NPC1 (0.34) HPGDTYMP
SCHEMBL8714271 0.84
SCHEMBL8713745 0.84
SCHEMBL8714191 0.83
SCHEMBL8714575 0.81 KDM4E (0.32) KDM4EALDH1A1GAAHPGDTYMP
SCHEMBL8714599 0.81 KDM4E (0.32) KDM4EALDH1A1GAAHPGDTYMP
SCHEMBL8717473 0.79

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5726336-A REACTING A BENZENE COMPOUND WITH A VINYLCHLOROSILANE COMPOUND IN THE PRESENCE OF A LEWIS ACID CATALYST; INTERMEDIATES FOR SILICONE POLYMERS USEFUL AS EMULSIONS, GREASES, ADHESIVES, SEALANTS, COATINGS, IN AUTOMOTIVE AND ENGINEERING FIELDS KOREA INSTITUTE OF SCIENCE AND TECHNOLOGY (KR) 1998-03-10 US disclosed