SCHEMBL8718699

SCHEMBL8718699

Cc1cn([C@H]2CC(O)[C@@H](COC(=O)OCCc3ccc(Cl)cc3[N+](=O)[O-])O2)c(=O)[nH]c1=O

nearest known ligand 0.53

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
POLB P06746 1/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7643477 1.00 POLB (0.47) POLB
SCHEMBL7646615 0.90 POLB (0.47) POLB
SCHEMBL8719350 0.90 POLB (0.47) POLB
SCHEMBL8719115 0.89 TK1 (0.51) POLB
SCHEMBL7644907 0.89 TK1 (0.51) POLB
SCHEMBL8722072 0.88 POLB (0.47) POLB
SCHEMBL7647587 0.88 POLB (0.47) POLB
SCHEMBL8723732 0.87 TYMS (0.48) POLB
SCHEMBL7643986 0.87 TYMS (0.48) POLB
SCHEMBL7643479 0.86 SLC29A1 (0.40)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5763599-A FOR LIGHT-CONTROLLED SYNTHESIS OF OLIGONUCLEOTIDES ON DNA CHIP Pfleiderer, Wolfgang (DE) 1998-06-09 US disclosed