SCHEMBL8718809

SCHEMBL8718809

CCCCc1cc(CC[Si](C)(Cl)Cl)c(CC[Si](C)(Cl)Cl)c(CC[Si](C)(Cl)Cl)c1CC[Si](C)(Cl)Cl

nearest known ligand 0.35

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CTRC Q99895 1/20 0.35
TYR P14679 1/20 0.34
TLR8 Q9NR97 1/20 0.33
NPC1 O15118 1/20 0.32
HPGD P15428 1/20 0.32
MAPK1 P28482 1/20 0.32
HTT P42858 1/20 0.32
RAB9A P51151 1/20 0.32
NPSR1 Q6W5P4 1/20 0.32
MEN1 O00255 1/20 0.31
KMT2A Q03164 1/20 0.31
GABRP O00591 1/20 0.31
GABRD O14764 1/20 0.31
GABRA1 P14867 1/20 0.31
GABRB1 P18505 1/20 0.31
GABRG2 P18507 1/20 0.31
GABRB3 P28472 1/20 0.31
GABRA5 P31644 1/20 0.31
GABRA3 P34903 1/20 0.31
GABRA2 P47869 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8714191 0.89
SCHEMBL8713264 0.88
SCHEMBL8719896 0.87 TYR (0.35) CTRCTYRTLR8NPC1HPGD
SCHEMBL8714958 0.85
SCHEMBL8716473 0.84 NPC1 (0.34) TLR8NPC1HPGDMAPK1HTT
SCHEMBL8713563 0.84 NPC1 (0.34) TLR8NPC1HPGDMAPK1HTT
SCHEMBL4632556 0.80 HTT (0.46) CTRCTYRTLR8NPC1HPGD
SCHEMBL8718854 0.77
SCHEMBL8718489 0.75 KDM4E (0.31) HPGD
SCHEMBL8718506 0.75 KDM4E (0.31) HPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5726336-A REACTING A BENZENE COMPOUND WITH A VINYLCHLOROSILANE COMPOUND IN THE PRESENCE OF A LEWIS ACID CATALYST; INTERMEDIATES FOR SILICONE POLYMERS USEFUL AS EMULSIONS, GREASES, ADHESIVES, SEALANTS, COATINGS, IN AUTOMOTIVE AND ENGINEERING FIELDS KOREA INSTITUTE OF SCIENCE AND TECHNOLOGY (KR) 1998-03-10 US disclosed