SCHEMBL8718840

SCHEMBL8718840

CCCN1C2COCC1CC(=NO)C2

nearest known ligand 0.47

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 1/20 0.33
HPGD P15428 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8715017 0.90 CHRM1 (0.32)
SCHEMBL8717542 0.89 OPRM1 (0.34)
SCHEMBL8716683 0.87 OPRM1 (0.36)
SCHEMBL8717612 0.82
SCHEMBL3410709 0.80 CHRNA7 (0.32)
SCHEMBL8714076 0.79
SCHEMBL8714030 0.78 CYP2D6 (0.33) ALDH1A1
SCHEMBL8719165 0.77 MAPK1 (0.39) ALDH1A1HPGD
SCHEMBL8719169 0.75 CHRNA7 (0.31)
SCHEMBL8717801 0.74 CHRNA7 (0.32)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0708105-B1 5-HT4 receptor agonists NISSHIN FLOUR MILLING CO (JP) 1998-12-23 EP disclosed
EP-0708105-A1 5-HT4 receptor agonists NISSHIN FLOUR MILLING CO., LTD. (JP) 1996-04-24 EP disclosed