Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A4 | P31645 | 7/20 | 0.49 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.49 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.49 |
| ▸ | MAOA | P21397 | 1/20 | 0.49 |
| ▸ | SLC2A1 | P11166 | 3/20 | 0.43 |
| ▸ | PNMT | P11086 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | ADRB1 | P08588 | 4/20 | 0.39 |
| ▸ | ADRB3 | P13945 | 4/20 | 0.39 |
| ▸ | ADRB2 | P07550 | 2/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8713870 | 0.86 | TAAR1 (0.47) | SLC6A2SLC6A3SLC2A1PNMTKDM4E | |
| SCHEMBL8716164 | 0.86 | SLC2A1 (0.45) | SLC6A2SLC6A3SLC2A1PNMTADRB1 | |
| SCHEMBL8716169 | 0.86 | SLC2A1 (0.45) | SLC6A2SLC6A3SLC2A1PNMTADRB1 | |
| SCHEMBL8717066 | 0.86 | SLC2A1 (0.45) | SLC6A2SLC6A3SLC2A1PNMTADRB1 | |
| SCHEMBL8713871 | 0.86 | TAAR1 (0.47) | SLC6A2SLC6A3SLC2A1PNMTKDM4E | |
| SCHEMBL8717068 | 0.86 | SLC2A1 (0.45) | SLC6A2SLC6A3SLC2A1PNMTADRB1 | |
| SCHEMBL8713862 | 0.86 | PNMT (0.50) | SLC6A4SLC6A2SLC6A3MAOASLC2A1 | |
| SCHEMBL8713991 | 0.85 | SLC6A4 (0.56) | SLC6A4MAOASLC2A1PNMTADRB1 | |
| SCHEMBL8714102 | 0.84 | KDM4E (0.56) | SLC6A4SLC6A2SLC6A3MAOAKDM4E | |
| SCHEMBL8714905 | 0.84 | ADRB3 (0.49) | SLC2A1PNMTADRB1ADRB3ADRB2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5811293-A | CULTURE PRODUCT AS CHEMICAL INTERMEDIATE FOR ANTI-OBESITY AGENT | DAICEL CHEMICAL INDUSTRIES, LTD. (JP) | 1998-09-22 | — | — | US | disclosed |