Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA9 | Q16790 | 11/20 | 0.79 |
| ▸ | CA12 | O43570 | 9/20 | 0.79 |
| ▸ | MCL1 | Q07820 | 6/20 | 0.79 |
| ▸ | AKR1B1 | P15121 | 5/20 | 0.79 |
| ▸ | HPGD | P15428 | 5/20 | 0.79 |
| ▸ | GAA | P10253 | 4/20 | 0.79 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.79 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.79 |
| ▸ | GLA | P06280 | 3/20 | 0.79 |
| ▸ | CASP1 | P29466 | 3/20 | 0.79 |
| ▸ | CASP7 | P55210 | 3/20 | 0.79 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.79 |
| ▸ | ERAP1 | Q9NZ08 | 3/20 | 0.79 |
| ▸ | LMNA | P02545 | 2/20 | 0.79 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.79 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.79 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.79 |
| ▸ | BCHE | P06276 | 1/20 | 0.79 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.79 |
| ▸ | MAPT | P10636 | 1/20 | 0.79 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Esculetin SCHEMBL8415100 | 0.94 | CA9 (0.70) | CA9CA12MCL1AKR1B1HPGD | |
| Esculetin SCHEMBL29569228 | 0.89 | CA9 (1.00) | CA9CA12MCL1AKR1B1HPGD | |
| Esculetin SCHEMBL24641 | 0.89 | CA9 (1.00) | CA9CA12MCL1AKR1B1HPGD | |
| Esculetin SCHEMBL6867015 | 0.89 | CA9 (1.00) | CA9CA12MCL1AKR1B1HPGD | |
| 3-Hydroxycoumarin SCHEMBL27436988 | 0.88 | HPGD (0.80) | CA9CA12MCL1AKR1B1HPGD | |
| Esculetin SCHEMBL8708221 | 0.87 | CA9 (0.96) | CA9CA12MCL1AKR1B1HPGD | |
| Esculetin SCHEMBL30120615 | 0.87 | CA9 (0.96) | CA9CA12MCL1AKR1B1HPGD | |
| Esculetin SCHEMBL1736697 | 0.87 | CA9 (0.96) | CA9CA12MCL1AKR1B1HPGD | |
| Esculetin SCHEMBL29163498 | 0.87 | CA9 (0.96) | CA9CA12MCL1AKR1B1HPGD | |
| Coumarin SCHEMBL27986957 | 0.85 | CA9 (0.80) | CA9CA12MCL1AKR1B1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0873444-A1 | ENZYMATIC METHOD FOR TEXTILE DYEING | Novo Nordisk Biochem North America (US) | 1998-10-28 | — | — | EP | disclosed |
| WO-1997023685-A1 | ENZYMATIC METHOD FOR TEXTILE DYEING | NOVO NORDISK BIOCHEM NORTH AMERICA, INC. (US) | 1997-07-03 | — | — | WO | disclosed |