Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A2 | P23975 | 2/20 | 0.39 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.39 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.39 |
| ▸ | IDO1 | P14902 | 2/20 | 0.38 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | AOC3 | Q16853 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.37 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.36 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8719255 | 1.00 | SLC6A2 (0.39) | SLC6A2SLC6A4SLC6A3CYP2D6CYP3A4 | |
| SCHEMBL8713784 | 0.91 | SLC6A2 (0.42) | SLC6A2SLC6A4SLC6A3CYP2D6CYP3A4 | |
| SCHEMBL8713787 | 0.91 | SLC6A2 (0.42) | SLC6A2SLC6A4SLC6A3CYP2D6CYP3A4 | |
| SCHEMBL8716176 | 0.91 | IDO1 (0.42) | SLC6A2SLC6A4CYP2D6KCNH2IDO1 | |
| SCHEMBL8716177 | 0.91 | IDO1 (0.42) | SLC6A2SLC6A4CYP2D6KCNH2IDO1 | |
| SCHEMBL8713608 | 0.89 | LMNA (0.39) | SLC6A2SLC6A4SLC6A3CYP2D6CYP3A4 | |
| SCHEMBL8713609 | 0.89 | LMNA (0.39) | SLC6A2SLC6A4SLC6A3CYP2D6CYP3A4 | |
| SCHEMBL8716628 | 0.88 | IDO1 (0.41) | SLC6A2SLC6A4CYP2D6KCNH2IDO1 | |
| SCHEMBL8716631 | 0.88 | IDO1 (0.41) | SLC6A2SLC6A4CYP2D6KCNH2IDO1 | |
| SCHEMBL8713907 | 0.86 | SLC6A2 (0.45) | SLC6A2SLC6A4SLC6A3CYP2D6CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5811293-A | CULTURE PRODUCT AS CHEMICAL INTERMEDIATE FOR ANTI-OBESITY AGENT | DAICEL CHEMICAL INDUSTRIES, LTD. (JP) | 1998-09-22 | — | — | US | disclosed |