Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.68 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.63 |
| ▸ | MEN1 | O00255 | 1/20 | 0.51 |
| ▸ | GAA | P10253 | 1/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.51 |
| ▸ | MAOA | P21397 | 1/20 | 0.51 |
| ▸ | MAOB | P27338 | 1/20 | 0.51 |
| ▸ | CA1 | P00915 | 7/20 | 0.48 |
| ▸ | CA2 | P00918 | 7/20 | 0.48 |
| ▸ | CA12 | O43570 | 6/20 | 0.48 |
| ▸ | CA9 | Q16790 | 6/20 | 0.48 |
| ▸ | STK17B | O94768 | 1/20 | 0.41 |
| ▸ | STK17A | Q9UEE5 | 1/20 | 0.41 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | DRD2 | P14416 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8021860 | 1.00 | CA14 (0.68) | CA14TDP1MEN1GAAKMT2A | |
| SCHEMBL13055412 | 0.97 | CA14 (0.64) | CA14TDP1MEN1GAAKMT2A | |
| SCHEMBL13055410 | 0.97 | CA14 (0.68) | CA14TDP1MEN1GAAKMT2A | |
| SCHEMBL8714161 | 0.97 | CA14 (0.68) | CA14TDP1MEN1GAAKMT2A | |
| SCHEMBL31329717 | 0.94 | TDP1 (0.69) | CA14TDP1MEN1GAAKMT2A | |
| SCHEMBL8020881 | 0.94 | CA14 (0.60) | CA14TDP1MEN1GAAKMT2A | |
| SCHEMBL13055400 | 0.94 | CA14 (0.64) | CA14TDP1MEN1GAAKMT2A | |
| SCHEMBL8850859 | 0.93 | CA14 (0.60) | CA14TDP1MEN1GAAKMT2A | |
| SCHEMBL14439576 | 0.93 | CA14 (0.60) | CA14TDP1MEN1GAAKMT2A | |
| SCHEMBL9885950 | 0.92 | CA14 (0.63) | CA14TDP1MEN1GAAKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0378146-A2 | Polyamine derivatives as antineoplastic agents | MERRELL PHARMACEUTICALS INC. (US) | 1990-07-18 | — | — | EP | claimed |
| EP-0490380-B1 | Use of N,N'-bis 3-(ethylamino)propyl -1,7-heptanediamine and a cytotoxic agent | MERRELL PHARMA INC (US) | 1998-02-18 | — | — | EP | disclosed |
| US-5654287-A | SYNERGISTIC | MERRELL PHAMACEUTICALS INC. (US) | 1997-08-05 | — | — | US | disclosed |
| US-5646124-A | ANTIBIOTIC | MERRELL PHARMACEUTICALS INC. (US) | 1997-07-08 | — | — | US | disclosed |
| US-5635218-A | ADMINISTERING WITH ANTINEOPLASTIC PLATINUM COORDINATION COMPLEX; SYNERGISTIC EFFECT | MERRELL PHARMACEUTICALS INC. (US) | 1997-06-03 | — | — | US | disclosed |
| US-5561136-A | USING VINBLASTINE AS SYNERGISTIC CYTOTOXIC AGENT | MERRELL PHARMACEUTICALS INC. (US) | 1996-10-01 | — | — | US | disclosed |
| EP-0662829-A1 | POLYAMINE DERIVATIVES AS ANTI-CYTOMEGALOVIRAL AGENTS | MERRELL PHARMACEUTICALS INC. (US) | 1995-07-19 | — | — | EP | disclosed |
| EP-0378146-B1 | Polyamine derivatives as antineoplastic agents | MERRELL DOW PHARMA (US) | 1995-03-29 | — | — | EP | disclosed |
| WO-1994007480-A1 | POLYAMINE DERIVATIVES AS ANTI-CYTOMEGALOVIRAL AGENTS | MERRELL DOW PHARMACEUTICALS INC. (US) | 1994-04-14 | — | — | WO | disclosed |
| EP-0490380-A2 | Use of N,N'-bis 3-(ethylamino)propyl -1,7-heptanediamine and a cytotoxic agent | MERRELL PHARMACEUTICALS INC. (US) | 1992-06-17 | — | — | EP | disclosed |
| US-5109024-A | Polyamine derivatives as antineoplastic agents | MERRELL DOW PHARMACEUTICALS INC. (US) | 1992-04-28 | — | — | US | disclosed |
| EP-0378146-A2 | Polyamine derivatives as antineoplastic agents | MERRELL PHARMACEUTICALS INC. (US) | 1990-07-18 | — | — | EP | disclosed |