⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28409399 | 1.00 | — | — | |
| SCHEMBL28412245 | 1.00 | — | — | |
| SCHEMBL224781 | 0.87 | — | — | |
| SCHEMBL2480097 | 0.85 | — | — | |
| SCHEMBL11757686 | 0.82 | PRKCA (0.38) | — | |
| SCHEMBL1437005 | 0.82 | MAPT (0.41) | — | |
| SCHEMBL28666266 | 0.81 | — | — | |
| SCHEMBL22747790 | 0.79 | PRKCA (0.42) | — | |
| SCHEMBL22556153 | 0.79 | — | — | |
| SCHEMBL8818137 | 0.79 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5912382-A | CARBAMYLATION BY REACTION OF AMINE WITH ALKYLENE CARBONATE IN THE PRESENCE CATALYST | HUNTSMAN PERTOCHEMICAL CORPORATION (US) | 1999-06-15 | — | — | US | claimed |
| US-4078146-A | TREATMENT OF CARDIO-VASCULAR DISORDERS | AKTIEBOLAGET HASSLE (SW) | 1978-03-07 | — | — | US | claimed |
| CN-117043145-A | Metal-containing and metal-free chiral TACN/NOTA compounds/derivatives for administration | 香港理工大学 | 2023-11-10 | — | — | CN | disclosed |
| CN-116848125-A | H4 antagonist compounds | 赫帕雷斯治疗有限公司 | 2023-10-03 | — | — | CN | disclosed |
| CN-115916790-A | Pyrido [2,3-b ] [1,4] oxazines or tetrahydropyrido [2,3-b ] [1,4] oxazepines as IAP antagonists | 百济神州有限公司 | 2023-04-04 | — | — | CN | disclosed |
| CN-113228201-B | Calpain-2selective inhibitor compounds for the treatment of glaucoma | 健康科学西部大学 | 2023-03-07 | — | — | CN | disclosed |
| EP-3938377-A1 | CYCLIC PEPTIDE ANTIBIOTICS | F. Hoffmann-La Roche AG (CH) | 2022-01-19 | — | — | EP | disclosed |
| CN-113228201-A | Calpain-2selective inhibitor compounds for the treatment of glaucoma | 健康科学西部大学 | 2021-08-06 | — | — | CN | disclosed |
| WO-2020185999-A1 | CYCLIC PEPTIDE ANTIBIOTICS | GENENTECH, INC. (US) | 2020-09-17 | — | — | WO | disclosed |
| CN-111303078-A | Synthesis method of tert-butyl 1,2, 3-thiazolidine-3-carboxylate 2, 2-dioxide compound | 苏州爱玛特生物科技有限公司 | 2020-06-19 | — | — | CN | disclosed |
| US-5912382-A | CARBAMYLATION BY REACTION OF AMINE WITH ALKYLENE CARBONATE IN THE PRESENCE CATALYST | HUNTSMAN PERTOCHEMICAL CORPORATION (US) | 1999-06-15 | — | — | US | disclosed |
| US-5912382-A | CARBAMYLATION BY REACTION OF AMINE WITH ALKYLENE CARBONATE IN THE PRESENCE CATALYST | HUNTSMAN PERTOCHEMICAL CORPORATION (US) | 1999-06-15 | — | — | US | disclosed |
| US-4078146-A | TREATMENT OF CARDIO-VASCULAR DISORDERS | AKTIEBOLAGET HASSLE (SW) | 1978-03-07 | — | — | US | disclosed |
| US-4035420-A | CARDIOVASCULAR DISORDERS | AKTIEBOLAGET HASSLE (SW) | 1977-07-12 | — | — | US | disclosed |