Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 8/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.57 |
| ▸ | HSD17B10 | Q99714 | 7/20 | 0.57 |
| ▸ | HPGD | P15428 | 5/20 | 0.57 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.51 |
| ▸ | TARBP2 | Q15633 | 2/20 | 0.50 |
| ▸ | CA1 | P00915 | 5/20 | 0.48 |
| ▸ | CA2 | P00918 | 5/20 | 0.48 |
| ▸ | PKM | P14618 | 1/20 | 0.47 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.47 |
| ▸ | SLC9A1 | P19634 | 1/20 | 0.46 |
| ▸ | CA12 | O43570 | 3/20 | 0.46 |
| ▸ | CA9 | Q16790 | 3/20 | 0.46 |
| ▸ | CA14 | Q9ULX7 | 2/20 | 0.46 |
| ▸ | MAOA | P21397 | 1/20 | 0.46 |
| ▸ | MAOB | P27338 | 1/20 | 0.46 |
| ▸ | TOP2A | P11388 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.45 |
| ▸ | NPC1 | O15118 | 2/20 | 0.45 |
| ▸ | MAPT | P10636 | 2/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8572041 | 0.82 | TARBP2 (0.49) | KDM4EALDH1A1HSD17B10HPGDTARBP2 | |
| SCHEMBL31687993 | 0.78 | IKBKB (0.68) | KDM4EALDH1A1HSD17B10HPGDMAPK1 | |
| SCHEMBL2778345 | 0.76 | TARBP2 (0.70) | KDM4EALDH1A1HSD17B10HPGDMAPK1 | |
| SCHEMBL7065162 | 0.76 | KDM4E (0.68) | KDM4EALDH1A1HSD17B10HPGDMAPK1 | |
| SCHEMBL13007418 | 0.73 | KDM4E (0.63) | KDM4EALDH1A1HSD17B10HPGDMAPK1 | |
| SCHEMBL14504405 | 0.73 | KDM4E (0.63) | KDM4EALDH1A1HSD17B10HPGDMAPK1 | |
| SCHEMBL13007419 | 0.73 | KDM4E (0.63) | KDM4EALDH1A1HSD17B10HPGDMAPK1 | |
| SCHEMBL2775823 | 0.72 | KDM4E (0.61) | KDM4EALDH1A1HSD17B10HPGDMAPK1 | |
| SCHEMBL28793572 | 0.72 | KDM4E (0.61) | KDM4EALDH1A1HSD17B10HPGDMAPK1 | |
| SCHEMBL8890199 | 0.71 | IKBKB (0.61) | KDM4EALDH1A1HSD17B10HPGDTARBP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5827869-A | Substituted biphenyl isoxazole sulfonamides | BRISTOL-MYERS SQUIBB COMPANY (US) | 1998-10-27 | — | — | US | disclosed |