Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IKBKB | O14920 | 9/20 | 0.61 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.59 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.59 |
| ▸ | PPARG | P37231 | 1/20 | 0.59 |
| ▸ | NCOA2 | Q15596 | 1/20 | 0.59 |
| ▸ | SLC9A1 | P19634 | 2/20 | 0.57 |
| ▸ | TARBP2 | Q15633 | 2/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL167906 | 0.81 | IKBKB (0.69) | IKBKBKDM4EHSD17B10PPARGNCOA2 | |
| SCHEMBL3124862 | 0.76 | IKBKB (0.71) | IKBKBKDM4EHSD17B10PPARGNCOA2 | |
| SCHEMBL31061359 | 0.76 | IKBKB (1.00) | IKBKBKDM4EHSD17B10PPARGNCOA2 | |
| SCHEMBL8890964 | 0.75 | KDM4E (1.00) | IKBKBKDM4EHSD17B10PPARGNCOA2 | |
| SCHEMBL8891206 | 0.73 | POLB (0.38) | IKBKBKDM4EHSD17B10PPARGNCOA2 | |
| SCHEMBL6630014 | 0.73 | FBP1 (0.36) | IKBKBSLC9A1 | |
| SCHEMBL7157388 | 0.72 | KDM4E (0.47) | KDM4EHSD17B10PPARGSLC9A1TARBP2 | |
| SCHEMBL3124515 | 0.72 | IKBKB (0.65) | IKBKBKDM4EHSD17B10PPARGNCOA2 | |
| SCHEMBL31198739 | 0.72 | IKBKB (0.63) | IKBKBKDM4EHSD17B10PPARGNCOA2 | |
| SCHEMBL8719982 | 0.71 | KDM4E (0.57) | IKBKBKDM4EHSD17B10PPARGNCOA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1997024340-A1 | OXAZOLE DERIVATIVES, THEIR PRODUCTION AND USE | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1997-07-10 | — | — | WO | disclosed |