Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BDKRB2 | P30411 | 14/20 | 0.49 |
| ▸ | HDAC3 | O15379 | 5/20 | 0.37 |
| ▸ | HDAC1 | Q13547 | 5/20 | 0.37 |
| ▸ | HDAC2 | Q92769 | 5/20 | 0.37 |
| ▸ | NCOR2 | Q9Y618 | 1/20 | 0.36 |
| ▸ | MMP1 | P03956 | 1/20 | 0.33 |
| ▸ | MMP2 | P08253 | 1/20 | 0.33 |
| ▸ | MMP9 | P14780 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7012869 | 0.88 | BDKRB2 (0.64) | BDKRB2HDAC3HDAC1HDAC2NCOR2 | |
| SCHEMBL7012866 | 0.88 | BDKRB2 (0.64) | BDKRB2HDAC3HDAC1HDAC2NCOR2 | |
| SCHEMBL8719999 | 0.75 | BDKRB2 (0.46) | BDKRB2HDAC3HDAC1HDAC2NCOR2 | |
| SCHEMBL7014771 | 0.73 | BDKRB2 (0.48) | BDKRB2 | |
| SCHEMBL7014777 | 0.73 | BDKRB2 (0.48) | BDKRB2 | |
| SCHEMBL8719661 | 0.73 | BDKRB2 (0.42) | BDKRB2 | |
| SCHEMBL7010790 | 0.72 | BDKRB2 (0.53) | BDKRB2 | |
| SCHEMBL7010789 | 0.72 | BDKRB2 (0.53) | BDKRB2 | |
| SCHEMBL6641008 | 0.71 | BDKRB2 (0.64) | BDKRB2 | |
| SCHEMBL7012873 | 0.70 | BDKRB2 (0.48) | BDKRB2HDAC3HDAC1HDAC2NCOR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0861243-A1 | HETEROCYCLIC COMPOUNDS AS BRADYKININ ANTAGONISTS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1998-09-02 | — | — | EP | disclosed |
| WO-1997011069-A1 | HETEROCYCLIC COMPOUNDS AS BRADYKININ ANTAGONISTS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1997-03-27 | — | — | WO | disclosed |