Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | IGF1R | P08069 | 1/20 | 0.34 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 2/20 | 0.32 |
| ▸ | NPC1 | O15118 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
| ▸ | STAT1 | P42224 | 1/20 | 0.30 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.30 |
| ▸ | TSHR | P16473 | 1/20 | 0.30 |
| ▸ | BAZ2A | Q9UIF9 | 1/20 | 0.30 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.30 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6089103 | 0.77 | ALDH1A1 (0.38) | ALDH1A1POLBKMT2ACYP2C9CYP2C19 | |
| SCHEMBL15380984 | 0.72 | ALDH1A1 (0.36) | ALDH1A1POLBKMT2AIGF1RCYP2C9 | |
| SCHEMBL5838930 | 0.66 | NPSR1 (0.43) | ALDH1A1CYP2C9CYP2C19CYP1A2RAB9A | |
| SCHEMBL8840819 | 0.66 | MAPK1 (0.47) | ALDH1A1POLBKMT2ACYP2C9CYP1A2 | |
| SCHEMBL15331650 | 0.65 | MAPK1 (0.52) | ALDH1A1POLBKMT2ACYP2C9CYP2C19 | |
| SCHEMBL6273007 | 0.65 | ALDH1A1 (0.45) | ALDH1A1POLBKMT2ACYP2C9CYP2C19 | |
| SCHEMBL4199341 | 0.65 | ALDH1A1 (0.65) | ALDH1A1POLBKMT2AIGF1RCYP2C9 | |
| SCHEMBL8686614 | 0.63 | KDM4E (0.38) | ALDH1A1POLBCYP2C9CYP2C19CYP1A2 | |
| SCHEMBL29954782 | 0.63 | ALDH1A1 (0.37) | ALDH1A1POLBKMT2AIGF1RCYP2C9 | |
| SCHEMBL6740330 | 0.63 | FGFR1 (0.44) | HSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5733903-A | ANTITUMOR AGENTS WITH DIAMAGNETISM | BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM (US) | 1998-03-31 | — | — | US | disclosed |