SCHEMBL8720069

SCHEMBL8720069

FC(F)(F)C(F)(F)C(F)(F)C(F)(F)CCCCCCc1ccccc1C(OC(c1ccccc1)(c1ccccc1)c1ccccc1CCCCCCC(F)(F)C(F)(F)C(F)(F)C(F)(F)F)(c1ccccc1)c1ccccc1

nearest known ligand 0.32

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
CYSLTR2 Q9NS75 1/20 0.32
CYSLTR1 Q9Y271 1/20 0.32
HDAC1 Q13547 1/20 0.32
HDAC8 Q9BY41 1/20 0.32
GAA P10253 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8573629 0.92 CYSLTR2 (0.33) CYSLTR2CYSLTR1HDAC1HDAC8GAA
SCHEMBL8717577 0.89 IDO1 (0.32)
SCHEMBL9078476 0.81 PTPN2 (0.38) HDAC1HDAC8
SCHEMBL8569410 0.81 KIF11 (0.30)
SCHEMBL8566051 0.78
SCHEMBL8718996 0.77
SCHEMBL8718233 0.75
SCHEMBL8569418 0.75 KIF11 (0.46)
SCHEMBL417236 0.74 KIF11 (0.33)
SCHEMBL8573617 0.72 PTPN2 (0.40) HDAC1HDAC8

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5744678-A NICKEL COMPOUND, ORGANOPHOSPHORUS COMPOUND, ORGANOALUMINUM COMPOUND, CARBON-HALOGEN COMPOUNDS; CATALYST SELECTIVITY NIPPON OIL CO., LTD. (JP) 1998-04-28 US disclosed
EP-0758563-A1 OLEFIN OLIGOMERIZATION CATALYST AND PROCESS FOR THE PREPARATION OF OLEFIN OLIGOMER USING IT NIPPON OIL COMPANY, LTD. (JP) 1997-02-19 EP disclosed
US-5556821-A Catalyst component for the polymerization of olefins NIPPON OIL COMPANY, LIMITED (JP) 1996-09-17 US disclosed