Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4A | O75164 | 8/20 | 0.97 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.97 |
| ▸ | TET2 | Q6N021 | 1/20 | 0.97 |
| ▸ | DOHH | Q9BU89 | 1/20 | 0.97 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.90 |
| ▸ | LMNA | P02545 | 1/20 | 0.90 |
| ▸ | GAA | P10253 | 1/20 | 0.90 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.90 |
| ▸ | PAOX | Q6QHF9 | 3/20 | 0.45 |
| ▸ | SLC6A5 | Q9Y345 | 2/20 | 0.43 |
| ▸ | KDM4C | Q9H3R0 | 7/20 | 0.39 |
| ▸ | CASP2 | P42575 | 1/20 | 0.37 |
| ▸ | KDM5A | P29375 | 1/20 | 0.36 |
| ▸ | KDM7A | Q6ZMT4 | 1/20 | 0.36 |
| ▸ | PHF8 | Q9UPP1 | 1/20 | 0.36 |
| ▸ | KDM2A | Q9Y2K7 | 1/20 | 0.36 |
| ▸ | NAAA | Q02083 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21051754 | 0.99 | KDM4A (1.00) | KDM4AHIF1ATET2DOHHKDM4E | |
| SCHEMBL26511991 | 0.99 | KDM4A (1.00) | KDM4AHIF1ATET2DOHHKDM4E | |
| SCHEMBL17100575 | 0.99 | KDM4A (1.00) | KDM4AHIF1ATET2DOHHKDM4E | |
| SCHEMBL17109729 | 0.99 | KDM4A (1.00) | KDM4AHIF1ATET2DOHHKDM4E | |
| SCHEMBL19040665 | 0.99 | KDM4A (1.00) | KDM4AHIF1ATET2DOHHKDM4E | |
| Deferoxamine SCHEMBL10498260 | 0.99 | KDM4A (1.00) | KDM4AHIF1ATET2DOHHKDM4E | |
| SCHEMBL13367139 | 0.99 | KDM4A (1.00) | KDM4AHIF1ATET2DOHHKDM4E | |
| Deferoxamine SCHEMBL34571 | 0.99 | KDM4A (1.00) | KDM4AHIF1ATET2DOHHKDM4E | |
| Deferoxamine SCHEMBL20658962 | 0.97 | KDM4A (0.97) | KDM4AHIF1ATET2DOHHKDM4E | |
| Deferoxamine SCHEMBL21049242 | 0.97 | KDM4A (0.97) | KDM4AHIF1ATET2DOHHKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1998020905-A2 | TREATMENT OF IRON OVERLOAD DISORDERS | BIOMEDICAL FRONTIERS, INC. (US) | 1998-05-22 | — | — | WO | disclosed |