SCHEMBL8720680

SCHEMBL8720680

CCCCOC=C(C)c1ccccc1

nearest known ligand 0.42

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
LTA4H P09960 2/20 0.42
LMNA P02545 2/20 0.41
PTGS2 P35354 1/20 0.41
CES2 O00748 3/20 0.40
CES1 P23141 3/20 0.40
TSHR P16473 3/20 0.40
TDP1 Q9NUW8 2/20 0.40
L3MBTL1 Q9Y468 2/20 0.40
HPGD P15428 1/20 0.37
RAB9A P51151 1/20 0.37
CYP1A2 P05177 1/20 0.37
CYP2C9 P11712 1/20 0.37
CYP2C19 P33261 1/20 0.37
NAAA Q02083 1/20 0.37
TP53 P04637 1/20 0.37
KDM4E B2RXH2 1/20 0.36
ALDH1A1 P00352 1/20 0.36
CYP3A4 P08684 1/20 0.36
MAPK1 P28482 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11007048 0.95 LTA4H (0.42) LTA4HLMNAPTGS2CES2CES1
SCHEMBL23244049 0.93 TSHR (0.42) LTA4HLMNACES2CES1TSHR
SCHEMBL23244077 0.93 TSHR (0.42) LTA4HLMNACES2CES1TSHR
SCHEMBL23244047 0.93 TSHR (0.42) LTA4HLMNACES2CES1TSHR
SCHEMBL23244072 0.93 TSHR (0.42) LTA4HLMNACES2CES1TSHR
SCHEMBL23244066 0.93 TSHR (0.42) LTA4HLMNACES2CES1TSHR
SCHEMBL23244070 0.93 TSHR (0.42) LTA4HLMNACES2CES1TSHR
SCHEMBL23244067 0.93 TSHR (0.42) LTA4HLMNACES2CES1TSHR
SCHEMBL23244079 0.93 TSHR (0.42) LTA4HLMNACES2CES1TSHR
Methane SCHEMBL27384727 0.92 LTA4H (0.40) LTA4HLMNAPTGS2CES2CES1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
JP-5320085-A None JP disclosed
CN-108472617-A Include the microcapsules of polyester-urethane shell and hydrophilic nuclear material 巴斯夫欧洲公司 2018-08-31 CN disclosed
WO-1998029396-A1 HETEROCYCLIC AROMATIC ANION SALTS, AND THEIR USES AS IONIC CONDUCTING MATERIALS HYDRO-QUEBEC (CA) 1998-07-09 WO disclosed
JP-H05320085-A P-TERTIARY BUTOXYPHENYLDIMETHYLCARBINOL AND ITS PRODUCTION HOKKO CHEM IND CO LTD 1993-12-03 JP disclosed