SCHEMBL8720707

SCHEMBL8720707

C1CCOCC1.C1CCOCC1.C1COCO1

nearest known ligand 0.61

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 1/20 0.61
TTR P02766 1/20 0.46
TSHR P16473 2/20 0.36
MEN1 O00255 1/20 0.32
KMT2A Q03164 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1890967 1.00 ALDH1A1 (0.61) ALDH1A1TTRTSHRMEN1KMT2A
Tetrahydrofuran SCHEMBL2360611 0.96 ALDH1A1 (0.67) ALDH1A1TTRTSHRMEN1KMT2A
SCHEMBL9539378 0.96 ALDH1A1 (0.67) ALDH1A1TTRTSHRMEN1KMT2A
SCHEMBL9050010 0.96 ALDH1A1 (0.67) ALDH1A1TTRTSHR
SCHEMBL7758217 0.96 ALDH1A1 (0.67) ALDH1A1TTRTSHRMEN1KMT2A
Tetrahydrofuran SCHEMBL23573614 0.96 ALDH1A1 (0.67) ALDH1A1TTRTSHRMEN1KMT2A
SCHEMBL11741977 0.96 ALDH1A1 (0.67) ALDH1A1TTRTSHR
Dioxane SCHEMBL5598923 0.96 ALDH1A1 (0.67) ALDH1A1TTRTSHRMEN1KMT2A
SCHEMBL3419841 0.92 ALDH1A1 (0.61) ALDH1A1TTRTSHR
SCHEMBL1080336 0.92

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2621923-B1 N-HETEROARYL COMPOUNDS WITH CYCLIC BRIDGING UNIT FOR THE TREATMENT OF PARASITIC DISEASES INTERVET INT BV (NL) 2017-03-29 EP claimed
US-5778515-A METHOD OF PREPARING AN ELECTRODE/SEPARATOR ASSEMBLY VALENCE TECHNOLOGY, INC. (US) 1998-07-14 US disclosed