SCHEMBL8720897

SCHEMBL8720897

COc1cc(C2=CC=CC(N)(OC)C2)ccc1N

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 4/20 0.50
CYP3A4 P08684 2/20 0.50
HSD17B10 Q99714 2/20 0.50
TSHR P16473 1/20 0.50
TDP1 Q9NUW8 1/20 0.50
APP P05067 4/20 0.36
CHEK1 O14757 7/20 0.34
HTT P42858 1/20 0.34
KDM4E B2RXH2 1/20 0.33
MEN1 O00255 1/20 0.33
POLB P06746 1/20 0.33
MAPT P10636 1/20 0.33
HPGD P15428 1/20 0.33
MAPK1 P28482 1/20 0.33
KMT2A Q03164 1/20 0.33
L3MBTL1 Q9Y468 1/20 0.33
QDPR P09417 1/20 0.32
GAK O14976 1/20 0.31
JAK2 O60674 1/20 0.31
PIK3CD O00329 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29399235 0.70 ALDH1A1 (1.00) ALDH1A1CYP3A4HSD17B10TSHRTDP1
SCHEMBL48945 0.70 ALDH1A1 (1.00) ALDH1A1CYP3A4HSD17B10TSHRTDP1
Methane SCHEMBL28975440 0.68 ALDH1A1 (0.95) ALDH1A1CYP3A4HSD17B10TSHRTDP1
Hydrochloric Acid SCHEMBL30053031 0.68 ALDH1A1 (0.95) ALDH1A1CYP3A4HSD17B10TSHRTDP1
Hydrochloric Acid SCHEMBL3947578 0.68 ALDH1A1 (0.95) ALDH1A1CYP3A4HSD17B10TSHRTDP1
Hydrochloric Acid SCHEMBL29494721 0.68 ALDH1A1 (0.95) ALDH1A1CYP3A4HSD17B10TSHRTDP1
Ammonia Solution, Strong SCHEMBL2259240 0.68 ALDH1A1 (0.95) ALDH1A1CYP3A4HSD17B10TSHRTDP1
Hydrochloric Acid SCHEMBL30913021 0.68 ALDH1A1 (0.95) ALDH1A1CYP3A4HSD17B10TSHRTDP1
Hydrochloric Acid SCHEMBL622811 0.68 ALDH1A1 (0.95) ALDH1A1CYP3A4HSD17B10TSHRTDP1
SCHEMBL27622453 0.68 ALDH1A1 (0.95) ALDH1A1CYP3A4HSD17B10TSHRTDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0648796-B1 Solutions of polyimide-forming substances and their use SCHENECTADY INT INC (US) 1998-08-26 EP disclosed
US-5493003-A MIXTURES OF AMINES, AMIDES AND/OR ESTERS OF TETRACARBOXYLIC ACIDS HAVING AMIDO OR ESTER GROUPS SUBSTITUTED WITH CARBOXYL, SULFO, SILYL OR SILOXY GROUPS, ELECTRONICS BASF LACKE + FARBEN AKTIENGESELLSCHAFT (DE) 1996-02-20 US disclosed
US-5478917-A Aromatic polyamines, tetracarboxylic acid amides and esters; smoothness, flexibility BASF LACKE + FARBEN AKTIENGESELLSCHAFT (DE) 1995-12-26 US disclosed
US-5474876-A Carboxyl-containing polymeric precursor of heterocyclic polymer which is stable at high temperatures and soluble in polar solvents, copolymerizable unsaturated tertiary sulfonium salt, photoinitiator, polar aprotic organic solvent BASF LACKE + FARBEN AG (DE) 1995-12-12 US disclosed
EP-0648796-A1 Solutions of polyimide-forming substances and their use BASF Lacke + Farben AG (DE) 1995-04-19 EP disclosed
EP-0648795-A1 Solutions of polyimide-forming substances and their use as coating material BASF Lacke + Farben AG (DE) 1995-04-19 EP disclosed
EP-0571899-B1 Radiation-curable mixture and its' use for producing high temperature-resistant relief structures BASF LACKE & FARBEN (DE) 1994-11-02 EP disclosed
EP-0573866-B1 Method for forming patterned layers of heat-resistant polycondensates BASF LACKE & FARBEN (DE) 1994-11-02 EP disclosed
US-5350663-A Construction of electrical circuits and protective or insulating layers for electronic components BASF LACKE+ FARBEN AKTIENGESELLSCHAFT (DE) 1994-09-27 US disclosed
EP-0573866-A1 Method for forming patterned layers of heat-resistant polycondensates BASF Lacke + Farben Aktiengesellschaft (DE) 1993-12-15 EP disclosed
EP-0571899-A1 Radiation-curable mixture and its' use for producing high temperature-resistant relief structures BASF Lacke + Farben Aktiengesellschaft (DE) 1993-12-01 EP disclosed