Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.46 |
| ▸ | GAA | P10253 | 2/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.45 |
| ▸ | KCNA5 | P22460 | 4/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.40 |
| ▸ | TBXAS1 | P24557 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25243987 | 0.82 | ALDH1A1 (0.46) | ALDH1A1KDM4EGAAKMT2AKCNA5 | |
| SCHEMBL28369254 | 0.82 | ALDH1A1 (0.47) | ALDH1A1KDM4EGAAKMT2AKCNA5 | |
| SCHEMBL9114061 | 0.82 | CYP2C19 (0.67) | ALDH1A1KMT2ACYP2C19MEN1LMNA | |
| SCHEMBL7506734 | 0.81 | ALDH1A1 (0.45) | ALDH1A1KDM4EGAAKMT2AKCNA5 | |
| SCHEMBL30479398 | 0.80 | KCNA5 (0.42) | ALDH1A1KDM4EGAAKMT2ACYP2C19 | |
| SCHEMBL31655316 | 0.78 | ALDH1A1 (0.48) | ALDH1A1KDM4EGAAKMT2AKCNA5 | |
| SCHEMBL25305283 | 0.78 | ALDH1A1 (0.48) | ALDH1A1KDM4EGAAKMT2AKCNA5 | |
| SCHEMBL9034087 | 0.76 | ALDH1A1 (0.50) | ALDH1A1GAAKMT2ATBXAS1MEN1 | |
| SCHEMBL9313982 | 0.76 | ALDH1A1 (0.51) | ALDH1A1KDM4EGAAKMT2AKCNA5 | |
| SCHEMBL14445303 | 0.75 | GAA (0.47) | ALDH1A1KDM4EGAAKMT2AMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0870768-A1 | Azaindole-ethylamine derivatives as nicotinic acetylcholine receptor binding agents | PFIZER INC. (US) | 1998-10-14 | — | — | EP | disclosed |