Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX2 | P34913 | 1/20 | 0.68 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.63 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.63 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.63 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.63 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.56 |
| ▸ | MEN1 | O00255 | 3/20 | 0.56 |
| ▸ | MAPT | P10636 | 3/20 | 0.54 |
| ▸ | HTT | P42858 | 1/20 | 0.54 |
| ▸ | BCL2 | P10415 | 1/20 | 0.54 |
| ▸ | LMNA | P02545 | 1/20 | 0.53 |
| ▸ | PRMT1 | Q99873 | 1/20 | 0.51 |
| ▸ | GAA | P10253 | 1/20 | 0.51 |
| ▸ | RAB9A | P51151 | 2/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.50 |
| ▸ | NPY1R | P25929 | 1/20 | 0.49 |
| ▸ | NPY2R | P49146 | 1/20 | 0.49 |
| ▸ | CA12 | O43570 | 2/20 | 0.49 |
| ▸ | CA1 | P00915 | 2/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28453476 | 0.84 | HDAC8 (0.68) | KMT2AMEN1 | |
| SCHEMBL1516167 | 0.81 | EPHX2 (1.00) | EPHX2KMT2AMEN1MAPTHTT | |
| SCHEMBL5623718 | 0.81 | CYP1A2 (0.65) | EPHX2CYP1A2CYP2D6CYP2C9CYP2C19 | |
| SCHEMBL28762298 | 0.81 | CA12 (0.70) | EPHX2CYP1A2CYP2D6CYP2C9CYP2C19 | |
| Hydrochloric Acid SCHEMBL27735879 | 0.80 | EPHX2 (0.96) | EPHX2KMT2AMEN1MAPTHTT | |
| SCHEMBL4433537 | 0.79 | CYP1A2 (0.67) | EPHX2CYP1A2CYP2D6CYP2C9CYP2C19 | |
| SCHEMBL5175200 | 0.79 | EPHX2 (0.79) | EPHX2KMT2AMEN1MAPTPRMT1 | |
| SCHEMBL5582937 | 0.78 | BCHE (0.55) | EPHX2KMT2AMEN1MAPTPRMT1 | |
| SCHEMBL7289139 | 0.78 | EPHX2 (0.60) | EPHX2CYP1A2CYP2D6CYP2C9CYP2C19 | |
| SCHEMBL10054999 | 0.77 | EPHX2 (0.92) | EPHX2KMT2AMEN1MAPTPRMT1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0745154-B1 | MULTICOMPONENT SYSTEM FOR MODIFYING, DECOMPOSING OR BLEACHING LIGNIN, LIGNIN-CONTAINING MATERIALS OR SIMILAR SUBSTANCES AND METHOD OF USING THIS SYSTEM | LIGNOZYM GMBH (DE) | 1998-09-16 | — | — | EP | claimed |