Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARG | P37231 | 10/20 | 0.51 |
| ▸ | ALOX5 | P09917 | 2/20 | 0.51 |
| ▸ | PTGES | O14684 | 1/20 | 0.51 |
| ▸ | PPARA | Q07869 | 10/20 | 0.47 |
| ▸ | CTRC | Q99895 | 1/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.44 |
| ▸ | CNR2 | P34972 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | CA2 | P00918 | 1/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11577652 | 0.94 | CTRC (0.52) | PPARGALOX5PTGESPPARACTRC | |
| SCHEMBL11617518 | 0.94 | CTRC (0.52) | PPARGALOX5PTGESPPARACTRC | |
| SCHEMBL11858517 | 0.89 | PPARG (0.50) | PPARGALOX5PTGESPPARACTRC | |
| SCHEMBL5210592 | 0.89 | TDP1 (0.54) | PPARGALOX5PTGESPPARACTRC | |
| SCHEMBL8935884 | 0.87 | PPARG (0.64) | PPARGALOX5PTGESPPARACTRC | |
| SCHEMBL289442 | 0.87 | PPARG (0.64) | PPARGALOX5PTGESPPARACTRC | |
| SCHEMBL7248945 | 0.86 | PPARG (0.51) | PPARGALOX5PTGESPPARACTRC | |
| SCHEMBL28003097 | 0.86 | PPARG (0.51) | PPARGALOX5PTGESPPARACTRC | |
| SCHEMBL11617523 | 0.84 | CTRC (0.47) | PPARGALOX5PTGESPPARACTRC | |
| SCHEMBL11577658 | 0.84 | CTRC (0.47) | PPARGALOX5PTGESPPARACTRC |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0886641-A2 | SYNTHESIS OF METHOXY NUCLEOSIDES AND ENZYMATIC NUCLEIC ACID MOLECULES | RIBOZYME PHARMACEUTICALS, INC. (US) | 1998-12-30 | — | — | EP | disclosed |
| WO-1997026270-A2 | SYNTHESIS OF METHOXY NUCLEOSIDES AND ENZYMATIC NUCLEIC ACID MOLECULES | RIBOZYME PHARMACEUTICALS, INC. (US) | 1997-07-24 | — | — | WO | disclosed |