Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC3 | O15379 | 2/20 | 0.54 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.54 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.54 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.54 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.54 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.54 |
| ▸ | HTT | P42858 | 1/20 | 0.54 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.52 |
| ▸ | MEN1 | O00255 | 1/20 | 0.52 |
| ▸ | LMNA | P02545 | 1/20 | 0.52 |
| ▸ | POLB | P06746 | 1/20 | 0.52 |
| ▸ | BLM | P54132 | 1/20 | 0.52 |
| ▸ | EGFR | P00533 | 5/20 | 0.51 |
| ▸ | MMP1 | P03956 | 2/20 | 0.50 |
| ▸ | MMP2 | P08253 | 2/20 | 0.50 |
| ▸ | MMP9 | P14780 | 2/20 | 0.50 |
| ▸ | MAOA | P21397 | 1/20 | 0.50 |
| ▸ | MAOB | P27338 | 1/20 | 0.50 |
| ▸ | HAO1 | Q9UJM8 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7654779 | 0.84 | HDAC3 (0.58) | HDAC3HDAC4HDAC1HDAC2HDAC8 | |
| SCHEMBL6971897 | 0.83 | TDP1 (0.65) | HDAC3HDAC4HDAC1HDAC2HDAC8 | |
| SCHEMBL7661457 | 0.81 | KMT2A (0.55) | HDAC3HDAC4HDAC1HDAC2HDAC8 | |
| SCHEMBL4029206 | 0.79 | HDAC2 (0.76) | HDAC3HDAC4HDAC1HDAC2HDAC8 | |
| SCHEMBL29060766 | 0.79 | HDAC2 (0.76) | HDAC3HDAC4HDAC1HDAC2HDAC8 | |
| SCHEMBL7662674 | 0.78 | HDAC2 (0.63) | HDAC3HDAC4HDAC1HDAC2HDAC8 | |
| Cinnamic Acid SCHEMBL28879066 | 0.78 | HDAC3 (0.70) | HDAC3HDAC4HDAC1HDAC2HDAC8 | |
| SCHEMBL975479 | 0.78 | KMT2A (0.69) | HDAC3HDAC4HDAC1HDAC2HDAC8 | |
| SCHEMBL7668482 | 0.78 | HDAC3 (0.63) | HDAC3HDAC4HDAC1HDAC2HDAC8 | |
| SCHEMBL975477 | 0.78 | KMT2A (0.69) | HDAC3HDAC4HDAC1HDAC2HDAC8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0861243-A1 | HETEROCYCLIC COMPOUNDS AS BRADYKININ ANTAGONISTS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1998-09-02 | — | — | EP | disclosed |
| WO-1997011069-A1 | HETEROCYCLIC COMPOUNDS AS BRADYKININ ANTAGONISTS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1997-03-27 | — | — | WO | disclosed |