SCHEMBL975479

SCHEMBL975479

CCNC(=O)C=Cc1ccccc1

nearest known ligand 0.69

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 2/20 0.69
MMP1 P03956 3/20 0.67
MMP2 P08253 3/20 0.67
MMP9 P14780 3/20 0.67
EGFR P00533 3/20 0.67
SLC6A19 Q695T7 1/20 0.67
HDAC3 O15379 3/20 0.63
HDAC1 Q13547 2/20 0.63
HDAC2 Q92769 2/20 0.63
HDAC4 P56524 1/20 0.63
HDAC8 Q9BY41 1/20 0.63
HDAC6 Q9UBN7 1/20 0.63
POLB P06746 1/20 0.63
RECQL P46063 1/20 0.63
ALDH1A1 P00352 3/20 0.59
RAB9A P51151 2/20 0.59
NPC1 O15118 1/20 0.59
SMN1; SMN2 Q16637 1/20 0.58
MAOA P21397 1/20 0.58
MAOB P27338 1/20 0.58

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL975477 1.00 KMT2A (0.69) KMT2AMMP1MMP2MMP9EGFR
SCHEMBL8099537 0.88 KMT2A (0.58) KMT2AMMP1MMP2MMP9EGFR
SCHEMBL14080852 0.88 HDAC3 (0.67) KMT2AMMP1MMP2MMP9EGFR
N-Propylcinnamamide SCHEMBL29040560 0.86 EGFR (0.77) KMT2AMMP1MMP2MMP9EGFR
N-Propylcinnamamide SCHEMBL28438139 0.86 EGFR (0.77) KMT2AMMP1MMP2MMP9EGFR
N-Propylcinnamamide SCHEMBL12224106 0.86 EGFR (0.77) KMT2AMMP1MMP2MMP9EGFR
SCHEMBL11590847 0.85 KMT2A (0.86) KMT2AMMP1MMP2MMP9EGFR
SCHEMBL25510259 0.85 KMT2A (0.73) KMT2AMMP1MMP2MMP9EGFR
Catechol SCHEMBL28831689 0.84 MMP1 (0.62) KMT2AMMP1MMP2MMP9SLC6A19
SCHEMBL8661061 0.84 MAOB (0.69) MMP1MMP2MMP9SLC6A19HDAC3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 20 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-108794691-A Non-crosslinked polyolefin composition for cable 重庆文理学院 2018-11-13 CN claimed
JP-4828407-B2 2011-11-30 JP claimed
EP-1594869-A2 3-SUBSTITUTED-2(ARYLALKYL)-1-AZABICYCLOALKANES AND METHODS OF USE THEREOF Targacept, Inc. (US) 2005-11-16 EP claimed
WO-2004076449-A2 3-SUBSTITUTED-2(ARYLALKYL)-1-AZABICYCLOALKANES AND METHODS OF USE THEREOF TARGACEPT, INC. (US) 2004-09-10 WO claimed
CN-113462278-B Varnish composition, method for producing polyimide resin, and additive 东京应化工业株式会社 2024-06-07 CN disclosed
CN-115093373-A 1, 5-disubstituted-3-fluoroalkyl-1, 2, 4-triazole compound and preparation method and application thereof 江苏省中国科学院植物研究所 2022-09-23 CN disclosed
CN-113462278-A Varnish composition, method for producing polyimide resin, and additive 东京应化工业株式会社 2021-10-01 CN disclosed
CN-106496411-B A kind of purposes of the hydrophobic associated polymer with a variety of ring structure side chains and preparation method thereof with it 中国海洋大学 2018-11-23 CN disclosed
EP-2994470-A1 QUINOLONE DERIVATIVES AS FIBROBLAST GROWTH FACTOR INHIBITORS Principia Biopharma Inc. (US) 2016-03-16 EP disclosed
WO-2014182829-A1 QUINOLONE DERIVATIVES AS FIBROBLAST GROWTH FACTOR INHIBITORS PRINCIPIA BIOPHARMA INC. (US) 2014-11-13 WO disclosed
EP-2268614-B1 METHOD FOR PRODUCING BETA-MERCAPTO CARBOXYLIC ACIDS SHOWA DENKO KK (JP) 2013-05-15 EP disclosed
US-8258340-B2 Method for producing β-mercapto carboxylic acids SHOWA DENKO K.K. (JP) 2012-09-04 US disclosed
US-20110015436-A1 METHOD FOR PRODUCING BETA-MERCAPTO CARBOXYLIC ACIDS SHOWA DENKO K.K. (JP) 2011-01-20 US disclosed
EP-2268614-A1 METHOD FOR PRODUCING BETA-MERCAPTO CARBOXYLIC ACIDS Showa Denko K.K. (JP) 2011-01-05 EP disclosed
WO-2009113711-A1 METHOD FOR PRODUCING -MERCAPTO CARBOXYLIC ACIDS SHOWA DENKO K.K. (JP) 2009-09-17 WO disclosed
US-20090131657-A1 PROCESS FOR ALKENYLATING CARBOXAMIDES BASF SE (DE) 2009-05-21 US disclosed
US-20050131101-A1 Ink composition and inkjet recording method FUJI PHOTO FILM CO., LTD. 2005-06-16 US disclosed
EP-1392644-A1 CINNAMIDE DERIVATIVES AS KCNQ POTASSIUM CHANNEL MODULATORS BRISTOL-MYERS SQUIBB COMPANY (US) 2004-03-03 EP disclosed
WO-2002096858-A1 CINNAMIDE DERIVATIVES AS KCNQ POTASSIUM CHANNEL MODULATORS BRISTOL-MYERS SQUIBB COMPANY (US) 2002-12-05 WO disclosed
CN-1026816-C Fluid dynamic bearing with continuous beam mounting bearing surface IDE RUSSELL D (US) 1994-11-30 CN disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20110015436-A1 METHOD FOR PRODUCING BETA-MERCAPTO CARBOXYLIC ACIDS CBS, ALDH7A1, CBR1 KMT2A 2360/4885MMP1 1901/4885MMP2 3854/4885
US-20090131657-A1 PROCESS FOR ALKENYLATING CARBOXAMIDES PRMT5, CYC1, CBR3 KMT2A 41/4885MMP1 4446/4885MMP2 4524/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.