Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE4A | P27815 | 17/20 | 0.50 |
| ▸ | PDE4B | Q07343 | 17/20 | 0.50 |
| ▸ | PDE4C | Q08493 | 17/20 | 0.50 |
| ▸ | PDE4D | Q08499 | 17/20 | 0.50 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.47 |
| ▸ | TSHR | P16473 | 1/20 | 0.45 |
| ▸ | TP53 | P04637 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8722564 | 0.96 | TSHR (0.51) | PDE4APDE4BPDE4CPDE4DMAPK1 | |
| SCHEMBL8719072 | 0.91 | PDE4A (0.49) | PDE4APDE4BPDE4CPDE4DTSHR | |
| SCHEMBL8719068 | 0.91 | PDE4A (0.49) | PDE4APDE4BPDE4CPDE4DTSHR | |
| SCHEMBL9127284 | 0.79 | ABCG2 (0.54) | PDE4APDE4BPDE4CPDE4DTSHR | |
| SCHEMBL9127287 | 0.79 | ABCG2 (0.54) | PDE4APDE4BPDE4CPDE4DTSHR | |
| SCHEMBL4826027 | 0.77 | PDE4A (0.66) | PDE4APDE4BPDE4CPDE4DMAPK1 | |
| SCHEMBL4819418 | 0.77 | PDE4A (0.66) | PDE4APDE4BPDE4CPDE4DMAPK1 | |
| SCHEMBL4181181 | 0.77 | MAPK1 (0.60) | PDE4APDE4BPDE4CPDE4DMAPK1 | |
| SCHEMBL27702999 | 0.77 | PDE4A (0.62) | PDE4APDE4BPDE4CPDE4DMAPK1 | |
| SCHEMBL4817920 | 0.76 | PDE4A (0.68) | PDE4APDE4BPDE4CPDE4DMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0860438-A1 | Fluorine-containing diphenyl acrylamide antimicrobial agents | Shenyang Research Institute of Chemical Industry (CN) | 1998-08-26 | — | — | EP | disclosed |