Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE4A | P27815 | 4/20 | 0.49 |
| ▸ | PDE4B | Q07343 | 4/20 | 0.49 |
| ▸ | PDE4C | Q08493 | 4/20 | 0.49 |
| ▸ | PDE4D | Q08499 | 4/20 | 0.49 |
| ▸ | MAPT | P10636 | 2/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.45 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.45 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.45 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.45 |
| ▸ | TSHR | P16473 | 1/20 | 0.45 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.44 |
| ▸ | CA12 | O43570 | 1/20 | 0.44 |
| ▸ | CA1 | P00915 | 1/20 | 0.44 |
| ▸ | CA2 | P00918 | 1/20 | 0.44 |
| ▸ | CA4 | P22748 | 1/20 | 0.44 |
| ▸ | CA6 | P23280 | 1/20 | 0.44 |
| ▸ | CA7 | P43166 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8719068 | 1.00 | PDE4A (0.49) | PDE4APDE4BPDE4CPDE4DMAPT | |
| SCHEMBL8722564 | 0.91 | TSHR (0.51) | PDE4APDE4BPDE4CPDE4DMAPT | |
| SCHEMBL8722200 | 0.91 | PDE4A (0.50) | PDE4APDE4BPDE4CPDE4DTSHR | |
| SCHEMBL9127287 | 0.87 | ABCG2 (0.54) | PDE4APDE4BPDE4CPDE4DMAPT | |
| SCHEMBL9127284 | 0.87 | ABCG2 (0.54) | PDE4APDE4BPDE4CPDE4DMAPT | |
| SCHEMBL12182759 | 0.82 | PDE4A (0.70) | PDE4APDE4BPDE4CPDE4DMAPT | |
| SCHEMBL12182752 | 0.82 | PDE4A (0.70) | PDE4APDE4BPDE4CPDE4DMAPT | |
| SCHEMBL14217141 | 0.77 | PDE4A (0.66) | PDE4APDE4BPDE4CPDE4DALDH1A1 | |
| SCHEMBL9367554 | 0.74 | CA12 (0.62) | PDE4APDE4BPDE4CPDE4DMAPT | |
| SCHEMBL28111437 | 0.74 | PDE4A (0.59) | PDE4APDE4BPDE4CPDE4DALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0860438-A1 | Fluorine-containing diphenyl acrylamide antimicrobial agents | Shenyang Research Institute of Chemical Industry (CN) | 1998-08-26 | — | — | EP | disclosed |