SCHEMBL8722247

SCHEMBL8722247

Cc1cc(-n2ccnc2)c2cccc(OCCc3c(Cl)ccc(-n4cccc4CNC(=O)C=Cc4ccc(C(=O)NCc5ccccn5)cc4)c3Cl)c2n1

nearest known ligand 0.91

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
BDKRB2 P30411 20/20 0.91

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7015683 0.95 BDKRB2 (1.00) BDKRB2
SCHEMBL7015687 0.95 BDKRB2 (1.00) BDKRB2
SCHEMBL8722250 0.89 BDKRB2 (0.81) BDKRB2
SCHEMBL7009401 0.88 BDKRB2 (0.86) BDKRB2
SCHEMBL7009398 0.88 BDKRB2 (0.86) BDKRB2
SCHEMBL7007786 0.86 BDKRB2 (0.88) BDKRB2
SCHEMBL7007781 0.86 BDKRB2 (0.88) BDKRB2
SCHEMBL8014765 0.86 BDKRB2 (0.83) BDKRB2
SCHEMBL8014763 0.86 BDKRB2 (0.83) BDKRB2
SCHEMBL7012003 0.86 BDKRB2 (0.83) BDKRB2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0861243-A1 HETEROCYCLIC COMPOUNDS AS BRADYKININ ANTAGONISTS FUJISAWA PHARMACEUTICAL CO., LTD. (JP) 1998-09-02 EP disclosed
WO-1997011069-A1 HETEROCYCLIC COMPOUNDS AS BRADYKININ ANTAGONISTS FUJISAWA PHARMACEUTICAL CO., LTD. (JP) 1997-03-27 WO disclosed