SCHEMBL872226

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL871460	0.90	PDE4B (0.51)	PDE4BACVR1PRKAA2ACKR3CYP3A4
	SCHEMBL870373	0.90	PDE4B (0.44)	PDE4BACVR1PRKAA2TRPV4AVPR1B
	SCHEMBL871660	0.90	PDE4B (0.40)	PDE4BPRKAA2AVPR1BCYP3A4
	SCHEMBL870707	0.90	PDE4B (0.41)	PDE4BPRKAA2AVPR1BCYP3A4
	SCHEMBL871661	0.90	PDE4B (0.40)	PDE4BPRKAA2AVPR1BCYP3A4
	SCHEMBL870708	0.90	PDE4B (0.41)	PDE4BPRKAA2AVPR1BCYP3A4
	SCHEMBL870227	0.90	PDE4B (0.51)	PDE4BACVR1PRKAA2ACKR3
	SCHEMBL3023140	0.89	PDE4B (0.47)	PDE4BACVR1PRKAA2ACKR3AVPR1B
	SCHEMBL872131	0.88	PDE4B (0.50)	PDE4BACVR1PRKAA2ACKR3CYP3A4
	SCHEMBL873085	0.88	PDE4B (0.52)	PDE4BACVR1PRKAA2CYP3A4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.