Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABCB11 | O95342 | 2/20 | 0.48 |
| ▸ | HTT | P42858 | 2/20 | 0.48 |
| ▸ | GSDMD | P57764 | 2/20 | 0.48 |
| ▸ | CYP2E1 | P05181 | 1/20 | 0.48 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.48 |
| ▸ | LMNA | P02545 | 3/20 | 0.43 |
| ▸ | MMP1 | P03956 | 1/20 | 0.42 |
| ▸ | MMP2 | P08253 | 1/20 | 0.42 |
| ▸ | MMP3 | P08254 | 1/20 | 0.42 |
| ▸ | MMP8 | P22894 | 1/20 | 0.42 |
| ▸ | CA12 | O43570 | 4/20 | 0.36 |
| ▸ | CA9 | Q16790 | 4/20 | 0.36 |
| ▸ | CA1 | P00915 | 3/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | EHMT2 | Q96KQ7 | 3/20 | 0.35 |
| ▸ | EHMT1 | Q9H9B1 | 3/20 | 0.35 |
| ▸ | CA2 | P00918 | 3/20 | 0.35 |
| ▸ | CA4 | P22748 | 2/20 | 0.35 |
| ▸ | HTR1A | P08908 | 2/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL689389 | 0.97 | — | — | |
| Ammonia Solution, Strong SCHEMBL5692533 | 0.94 | — | — | |
| Water SCHEMBL163315 | 0.94 | ABCB11 (0.48) | ABCB11HTTGSDMDCYP2E1PTGS1 | |
| Selenium SCHEMBL1617421 | 0.94 | ABCB11 (0.48) | ABCB11HTTGSDMDCYP2E1PTGS1 | |
| SCHEMBL3504207 | 0.94 | — | — | |
| SCHEMBL6422366 | 0.91 | ABCB11 (0.46) | ABCB11HTTGSDMDCYP2E1PTGS1 | |
| SCHEMBL10901417 | 0.88 | HTT (0.43) | ABCB11HTTGSDMDCYP2E1PTGS1 | |
| Diethylamine SCHEMBL8672658 | 0.84 | ABCB11 (0.40) | ABCB11HTTGSDMDCYP2E1PTGS1 | |
| SCHEMBL6195760 | 0.80 | — | — | |
| SCHEMBL24452951 | 0.76 | ABCB11 (0.44) | ABCB11HTTGSDMDCYP2E1PTGS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5849392-A | Thread wound golf ball | SUMITOMO RUBBER INDUSTRIES, LTD. (JP) | 1998-12-15 | — | — | US | disclosed |
| EP-0192930-B1 | NATURAL RUBBER CONTAINING COMPOSITIONS WITH INCREASED TEAR STRENGTH | THE FIRESTONE TIRE & RUBBER COMPANY (US) | 1990-03-28 | — | — | EP | disclosed |
| EP-0139848-B1 | ELASTOMERIC COMPOSITION COMPRISING NATURAL RUBBER FOR USE UNDER DYNAMIC, HIGH HEAT CONDITIONS | THE FIRESTONE TIRE & RUBBER COMPANY (US) | 1988-03-02 | — | — | EP | disclosed |
| EP-0192930-A1 | Natural rubber containing compositions with increased tear strength | THE FIRESTONE TIRE & RUBBER COMPANY (US) | 1986-09-03 | — | — | EP | disclosed |
| US-4585826-A | CARBOXY-TERMINATED ACRYLONITRILE-BUTADIENE COPOLYMER | THE FIRESTONE TIRE & RUBBER COMPANY (US) | 1986-04-29 | — | — | US | disclosed |
| EP-0139848-A1 | Elastomeric composition comprising natural rubber for use under dynamic, high heat conditions | THE FIRESTONE TIRE & RUBBER COMPANY (US) | 1985-05-08 | — | — | EP | disclosed |
| US-4465829-A | ADDITION OF LOW MOLECULAR WEIGHT POLYISOBUTYLENE | THE FIRESTONE TIRE & RUBBER COMPANY (US) | 1984-08-14 | — | — | US | disclosed |