Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | APP | P05067 | 10/20 | 0.80 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.57 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.57 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.57 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.57 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.57 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.57 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.57 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.57 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.57 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.57 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.57 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.57 |
| ▸ | CYP2A13 | Q16696 | 1/20 | 0.57 |
| ▸ | MAPT | P10636 | 3/20 | 0.54 |
| ▸ | RELA | Q04206 | 1/20 | 0.53 |
| ▸ | HSD17B3 | P37058 | 1/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.50 |
| ▸ | METAP1 | P53582 | 2/20 | 0.50 |
| ▸ | MEN1 | O00255 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1044097 | 1.00 | APP (0.80) | APPHDAC3HDAC4HDAC1HDAC7 | |
| SCHEMBL1044099 | 1.00 | APP (0.80) | APPHDAC3HDAC4HDAC1HDAC7 | |
| SCHEMBL2559026 | 1.00 | APP (0.80) | APPHDAC3HDAC4HDAC1HDAC7 | |
| SCHEMBL11875807 | 1.00 | APP (0.80) | APPHDAC3HDAC4HDAC1HDAC7 | |
| SCHEMBL351371 | 0.92 | APP (0.72) | APPHDAC3HDAC4HDAC1HDAC7 | |
| SCHEMBL374619 | 0.92 | APP (0.72) | APPHDAC3HDAC4HDAC1HDAC7 | |
| Hydrochloric Acid SCHEMBL8508997 | 0.90 | APP (0.69) | APPHDAC3HDAC4HDAC1HDAC7 | |
| SCHEMBL2831927 | 0.89 | APP (1.00) | APPHDAC3HDAC4HDAC1HDAC7 | |
| SCHEMBL11876857 | 0.87 | APP (0.95) | APPHDAC3HDAC4HDAC1HDAC7 | |
| SCHEMBL9017239 | 0.87 | APP (0.95) | APPHDAC3HDAC4HDAC1HDAC7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5804101-A | ACCEPTOR AND DONAR GROUPS SELECTED FROM 5-PHENYL-3-ISOXAZOLONE GROUP AND DIARYLAMINOBENZENE OR CYCLIC AMINOBENZENE OR ARYLOXYBENZENE OR ARYLTHIOBENZENE; LASER BEAMS; THIN FILM OR A CRYSTAL | CALIFORNIA INSTITUTE OF TECHNOLOGY (US) | 1998-09-08 | — | — | US | disclosed |
| US-5670090-A | Nonlinear optical materials with reduced aromaticity and bond length alternation | CALIFORNIA INSTITUTE OF TECHNOLOGY (US) | 1997-09-23 | — | — | US | disclosed |
| US-5670091-A | Nonlinear optical materials with reduced aromaticity and bond length alternation | CALIFORNIA INSTITUTE OF TECHNOLOGY (US) | 1997-09-23 | — | — | US | disclosed |
| US-3947337-A | α,ω-Diarylpolyene photosensitizers for sulfonylazide polymers | THE UPJOHN COMPANY (US) | 1976-03-30 | — | — | US | disclosed |