Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | APP | P05067 | 7/20 | 0.95 |
| ▸ | RELA | Q04206 | 1/20 | 0.67 |
| ▸ | MAPT | P10636 | 5/20 | 0.66 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.63 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.63 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.63 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.63 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.63 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.63 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.63 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.63 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.63 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.63 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.63 |
| ▸ | MEN1 | O00255 | 3/20 | 0.61 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.61 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.61 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.61 |
| ▸ | CASP1 | P29466 | 2/20 | 0.61 |
| ▸ | HBB | P68871 | 2/20 | 0.61 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11876857 | 1.00 | APP (0.95) | APPRELAMAPTHDAC3HDAC4 | |
| SCHEMBL9017237 | 1.00 | APP (0.95) | APPRELAMAPTHDAC3HDAC4 | |
| SCHEMBL11876851 | 1.00 | APP (0.95) | APPRELAMAPTHDAC3HDAC4 | |
| SCHEMBL2831927 | 0.97 | APP (1.00) | APPRELAMAPTHDAC3HDAC4 | |
| SCHEMBL13050832 | 0.91 | APP (0.79) | APPRELAMAPTHDAC3HDAC4 | |
| SCHEMBL12267732 | 0.91 | APP (0.79) | APPRELAMAPTHDAC3HDAC4 | |
| SCHEMBL13467434 | 0.89 | RELA (0.81) | APPRELAMAPTMEN1KMT2A | |
| SCHEMBL7915381 | 0.89 | RELA (0.81) | APPRELAMAPTMEN1KMT2A | |
| SCHEMBL1714446 | 0.89 | RELA (0.81) | APPRELAMAPTMEN1KMT2A | |
| SCHEMBL3025040 | 0.89 | RELA (0.81) | APPRELAMAPTMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5486441-A | CHARGE TRANSPORT | TAKASAGO INTERNATIONAL CORPORATION (JP) | 1996-01-23 | — | — | US | disclosed |
| US-5463128-A | Charge transporting material | TAKASAGO INTERNATIONAL CORPORATION (JP) | 1995-10-31 | — | — | US | disclosed |