Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 3/20 | 0.35 |
| ▸ | TBXAS1 | P24557 | 2/20 | 0.33 |
| ▸ | NPC1 | O15118 | 5/20 | 0.32 |
| ▸ | RAB9A | P51151 | 5/20 | 0.32 |
| ▸ | HTT | P42858 | 5/20 | 0.32 |
| ▸ | GALR3 | O60755 | 2/20 | 0.32 |
| ▸ | POLB | P06746 | 2/20 | 0.32 |
| ▸ | ATM | Q13315 | 2/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.32 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | RAD52 | P43351 | 1/20 | 0.32 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.32 |
| ▸ | NR2F2 | P24468 | 1/20 | 0.32 |
| ▸ | APOBEC3A | P31941 | 1/20 | 0.32 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.32 |
| ▸ | NOD2 | Q9HC29 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8727757 | 1.00 | LMNA (0.35) | LMNATBXAS1NPC1RAB9AHTT | |
| SCHEMBL152255 | 0.92 | LMNA (0.33) | LMNAHTTATMMEN1KMT2A | |
| SCHEMBL6135368 | 0.83 | TP53 (0.34) | HTTMEN1KMT2ATP53 | |
| SCHEMBL27458343 | 0.75 | TP53 (0.46) | LMNATBXAS1NPC1RAB9AHTT | |
| SCHEMBL3741069 | 0.75 | LMNA (0.50) | LMNA | |
| SCHEMBL20478196 | 0.75 | LMNA (0.50) | LMNA | |
| SCHEMBL396922 | 0.75 | LMNA (0.50) | LMNA | |
| SCHEMBL20478198 | 0.75 | LMNA (0.50) | LMNA | |
| SCHEMBL6009511 | 0.75 | LMNA (0.50) | LMNA | |
| SCHEMBL399581 | 0.75 | LMNA (0.50) | LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0588237-B1 | 1-Pyrrolyl silicon compounds, chemically adsorbed ultrathin film formed therefrom and method of manufacturing the same | MATSUSHITA ELECTRIC INDUSTRIAL CO LTD (JP) | 1998-12-02 | — | — | EP | disclosed |