Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 3/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 2/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | KDM1A | O60341 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.38 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.38 |
| ▸ | SMO | Q99835 | 2/20 | 0.37 |
| ▸ | PPARD | Q03181 | 1/20 | 0.37 |
| ▸ | PPARA | Q07869 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10954783 | 0.92 | GAA (0.47) | GAAKDM4EALDH1A1TDP1SMN1; SMN2 | |
| SCHEMBL10950586 | 0.85 | GAA (0.43) | GAAKDM4EALDH1A1TDP1SMN1; SMN2 | |
| SCHEMBL9295944 | 0.82 | SMO (0.39) | GAAALDH1A1SMN1; SMN2LMNAHDAC1 | |
| SCHEMBL10335824 | 0.77 | MEN1 (0.43) | GAAKDM4EALDH1A1TDP1SMN1; SMN2 | |
| SCHEMBL10460433 | 0.77 | SMO (0.39) | GAASMN1; SMN2LMNAHDAC1HDAC6 | |
| SCHEMBL11337046 | 0.74 | MEN1 (0.41) | GAAKDM4EALDH1A1TDP1LMNA | |
| SCHEMBL1561553 | 0.74 | GAA (0.40) | GAAKDM4EALDH1A1TDP1SMN1; SMN2 | |
| SCHEMBL5075815 | 0.73 | MEN1 (0.41) | GAAKDM4EALDH1A1SMN1; SMN2LMNA | |
| SCHEMBL9295561 | 0.72 | KDM1A (0.43) | GAAALDH1A1SMN1; SMN2KDM1AMAPT | |
| SCHEMBL11354993 | 0.72 | SMN1; SMN2 (0.38) | GAAALDH1A1SMN1; SMN2LMNAMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5763191-A | BINDING MATRIX | BOEHRINGER MANNHEIM GMBH (DE) | 1998-06-09 | — | — | US | disclosed |
| EP-0515615-B1 | UNIVERSAL BINDING FILM | BOEHRINGER MANNHEIM GMBH (DE) | 1996-09-04 | — | — | EP | disclosed |