SCHEMBL5075815

SCHEMBL5075815

O=C1C(c2ccccc2)N(Cl)C(=O)N1c1ccccc1

nearest known ligand 0.43

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 3/20 0.41
KMT2A Q03164 3/20 0.41
MGLL Q99685 1/20 0.39
GAA P10253 4/20 0.39
MAOA P21397 1/20 0.39
POLB P06746 1/20 0.39
ATM Q13315 1/20 0.39
NPSR1 Q6W5P4 1/20 0.38
CACNA1B Q00975 1/20 0.38
APBA1 Q02410 1/20 0.38
ALDH1A1 P00352 2/20 0.37
MAPT P10636 2/20 0.37
GFER P55789 2/20 0.37
SMN1; SMN2 Q16637 1/20 0.37
MMP2 P08253 1/20 0.37
SMO Q99835 2/20 0.37
KDM4E B2RXH2 1/20 0.36
LMNA P02545 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2791034 0.80 NPSR1 (0.42) MEN1KMT2AMGLLGAAMAOA
SCHEMBL14353735 0.79 MEN1 (0.41) MEN1KMT2AMGLLGAAMAOA
SCHEMBL10335824 0.79 MEN1 (0.43) MEN1KMT2AMGLLGAAMAOA
SCHEMBL19923553 0.78 MAOA (0.42) MEN1KMT2AMGLLGAAMAOA
SCHEMBL11337046 0.76 MEN1 (0.41) MEN1KMT2AMGLLGAAMAOA
SCHEMBL10950586 0.76 GAA (0.43) MEN1KMT2AGAAALDH1A1SMN1; SMN2
SCHEMBL19923647 0.73 GAA (0.38) MEN1KMT2AMGLLGAAMAOA
SCHEMBL8722998 0.73 GAA (0.41) MEN1KMT2AGAAALDH1A1MAPT
SCHEMBL1639999 0.73 ALDH1A1 (0.47) MEN1KMT2AMGLLGAAMAOA
SCHEMBL9295944 0.72 SMO (0.39) MEN1KMT2AMGLLGAAMAOA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1968380-A2 SOLID BIOCIDE COMPOSITION AND SEALED BIOCIDE ARTICLE Sanderson, William D. (US) 2008-09-17 EP disclosed
WO-2007078838-A2 SOLID BIOCIDE COMPOSITION AND SEALED BIOCIDE ARTICLE SANDERSON WILLIAM D (US) 2007-07-12 WO disclosed