Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.48 |
| ▸ | HTT | P42858 | 1/20 | 0.48 |
| ▸ | GFER | P55789 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.48 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.48 |
| ▸ | EDNRB | P24530 | 6/20 | 0.47 |
| ▸ | EDNRA | P25101 | 6/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.46 |
| ▸ | TP53 | P04637 | 1/20 | 0.43 |
| ▸ | GLA | P06280 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22162939 | 0.85 | KMT2A (0.54) | MEN1HTTGFERKMT2AHSD17B10 | |
| SCHEMBL2039641 | 0.81 | CTSA (0.46) | ALDH1A1 | |
| SCHEMBL8406394 | 0.79 | TDP1 (0.51) | MEN1HTTKMT2AALDH1A1MAPT | |
| SCHEMBL8724571 | 0.79 | CYP1A2 (0.46) | EDNRBEDNRAALDH1A1MAPTLMNA | |
| SCHEMBL8871300 | 0.77 | ALDH1A1 (0.59) | HTTEDNRBEDNRAALDH1A1MAPT | |
| SCHEMBL9193808 | 0.77 | ALDH1A1 (0.52) | ALDH1A1 | |
| SCHEMBL9221970 | 0.75 | ALDH1A1 (0.62) | MEN1KMT2AALDH1A1TDP1 | |
| SCHEMBL9084059 | 0.75 | MEN1 (0.51) | MEN1KMT2AALDH1A1 | |
| SCHEMBL8720788 | 0.74 | CYP1A2 (0.56) | EDNRBEDNRAALDH1A1TP53LMNA | |
| SCHEMBL8584199 | 0.74 | KDM4E (0.51) | MEN1KMT2AEDNRBEDNRAALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0819679-A2 | Process for the preparation of pyrimidine-2-carboxylique acid esters | LONZA AG (CH) | 1998-01-21 | — | — | EP | disclosed |