Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DYRK1A | Q13627 | 1/20 | 0.42 |
| ▸ | HCAR2 | Q8TDS4 | 3/20 | 0.36 |
| ▸ | KIT | P10721 | 3/20 | 0.31 |
| ▸ | AKT2 | P31751 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | HTT | P42858 | 1/20 | 0.30 |
| ▸ | PTK2 | Q05397 | 1/20 | 0.30 |
| ▸ | CSNK2A2 | P19784 | 1/20 | 0.30 |
| ▸ | KDR | P35968 | 1/20 | 0.30 |
| ▸ | CSNK2B | P67870 | 1/20 | 0.30 |
| ▸ | CSNK2A1 | P68400 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL599727 | 0.77 | HCAR2 (0.45) | DYRK1AHCAR2KITCSNK2A2KDR | |
| SCHEMBL9123806 | 0.74 | HCAR2 (0.39) | HCAR2CSNK2A2KDRCSNK2BCSNK2A1 | |
| SCHEMBL4631308 | 0.70 | HCAR2 (0.63) | DYRK1AHCAR2 | |
| SCHEMBL6195861 | 0.68 | PDE4D (0.47) | DYRK1AAKT2CSNK2A2KDRCSNK2B | |
| SCHEMBL600381 | 0.67 | — | — | |
| Hydrochloric Acid SCHEMBL15550505 | 0.65 | — | — | |
| SCHEMBL20798457 | 0.65 | HCAR2 (0.42) | DYRK1AHCAR2KIT | |
| SCHEMBL459546 | 0.64 | DYRK1A (0.42) | DYRK1A | |
| SCHEMBL19158730 | 0.63 | PDE4D (0.59) | HCAR2KITKMT2A | |
| SCHEMBL14190551 | 0.62 | HCAR2 (0.44) | HCAR2CSNK2A2KDRCSNK2BCSNK2A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0879227-A1 | TYROSIN-DERIVATE AS ALPHA-V-INTEGRIN INHIBITORS | MERCK PATENT GmbH (DE) | 1998-11-25 | — | — | EP | disclosed |
| WO-1997023451-A1 | TYROSIN-DERIVATE AS ALPHA-V-INTEGRIN INHIBITORS | MERCK Patent Gesellschaft mit beschränkter Haftung (DE) | 1997-07-03 | — | — | WO | disclosed |